中心团队_生物医学光学与分子影像研究中心

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Principal Investigators

Song, Liang（宋亮）, PhD, Professor

Liang Song, Ph.D., is Professor at SIAT, CAS and founding directors of The Research Lab for Biomedical Optics, and The Shenzhen Key Lab for Molecular Imaging. Prior to joining SIAT, he studied at Washington University, St. Louis and received his Ph.D. in Biomedical Engineering. He has authored >40 peer-reviewed journal articles in Advanced Functional Materials, Optics Letters, Biomaterials etc., which have been cited by prestigious journals such as Science and Nature Medicine （as in 08/2016, total citations>850; h-index: 17）. He has invented and developed multiple novel photoacoustic imaging technologies and been awarded >10 US and Chinese invention patents, for example: (1) optical-resolution intravascular photoacoustic endomicroscopy aiming for the identification of vulnerable plaques; (2) fully integrated photoacoustic/two-photon microscopy that can potentially open up new avenues for multi-contrast sub-cellular biomedical imaging; (3) handheld, real-time photoacoustic imaging system for cancer theranostics. His research on photoacoustics has been supported by the NSFC (including the National Key Instrumentation R&D Grant and National Excellent Young Scholar Award), the MOST of China, the local governments, and the industry.

宋亮（个人主页），研究员，博士生导师。中科院深圳先进技术研究院生物医学光学研究中心荣誉主任，深圳分子影像学重点实验室主任。国家优秀青年科学基金、广东省首批科技创新青年拔尖人才及深圳市青年科技奖获得者。2003年毕业于武汉大学，后赴香港中文大学和美国学习，2010年毕业于美国华盛顿大学（Wash. Univ., St. Louis），获生物医学工程博士学位，导师为国际医学光声成像领域的开拓者汪立宏教授。目前担任中国生物医学工程学会青年工作委员会委员、生物医学光子学分会委员、中华医学会激光医学分会委员、中国科学院青年创新促进会会员。主持国家自然科学基金国家重大科研仪器研制（2014年全国共64项，资助率10%）、粤港合作，以及深圳市和企业的各级科研项目10余项。担任Elsevier出版的首个光声领域专业学术期刊Photoacoustics编委，以及IEEE TMI、Scientific Reports、Opt Lett等20余家国际著名SCI期刊审稿人；在Advanced Functional Materials等国际著名SCI期刊发表论文40余篇，被包括Science和Nature Medicine在内的知名期刊引用850余次（h指数17）；申请美国发明专利2项（授权1项），中国发明专利20余项（授权10项）。从事光学和超声医学成像技术的研发及相关医学应用研究超过10年，曾成功带领团队率先研发出光学分辨率的血管内光声成像系统；发明和研发了首台光声/双光子显微成像系统；研发了用于肿瘤淋巴转移无创成像的实时手持式光声成像系统，具有丰富的创新医疗技术研发和临床转化经验。

  • Tel：0755-86392240
  • Email：liang.song@siat.ac.cn;
  • Homepage：http://people.ucas.edu.cn/~lsong
    • Zheng, Wei（郑炜）, PhD, Professor

    Wei Zheng, Ph.D, professor, received his B.S. degree in Optical Engineering from Zhejiang University in 2003, his Ph.D. degree in Electronic and Computer Engineering from Hong Kong University of Science and Technology in 2011. His research focuses on biomedical optics, including fluorescence spectroscopy, fluorescence microscopy and nonlinear optical microscopy. He has developed a series of novel multi-photon excitation microscopy system to study the feasibility of noninvasive diagnosis of precancer based on the biological autofluorescence. For the first time, he discovered and demonstratedthat hemoglobin can emit the Soret autofluorescence via two-photon excitation.His current study is to develop novel biomedical imagingmethods that would aid in the understanding and diagnosis of various diseases, including cancer and cardiovascular diseases. He has authored and co-authored more than 40 journal and conference articles. He is a member of Optical Society of America, a senior member of Chinese Optical Society and a senior member of Chinese Society of Biomedical Engineering.

    郑炜（个人主页），研究员，博士生导师，中科院深圳先进技术研究院生物医学与健康工程研究所所长助理，生物医学光学与分子影像研究中心主任，国家自然科学基金“优青青年”基金获得者，广东省“特支计划”科技创新领军人才，深圳市“孔雀计划”海外高层次人才。2011年博士毕业于香港科技大学电机及电子工程系，并于同年加入中科院深圳先进技术研究院任副研究员，2016年晋升研究员。主要研究方向为生物医学光子学及光学显微成像技术研究。已发表学术论文40余篇，其中作为一作或通讯作者发表Nature Methods, Optics letters等期刊论文10余篇。已申请专利15项，授权专利10项。作为项目负责人主持了科技部重点研发计划数字诊疗专项、国家自然科学基金优青、面上、青年等项目。

  • Tel：0755-86392240
  • Email：zhengwei@siat.ac.cn
  • Homepage：http://people.ucas.edu.cn/~zhengw80
    • Chu, Jun（储军）, PhD, Professor

    Jun Chu received his Ph.D. degree in Biomedical Engineering from Wuhan National Laboratory for Optoelectronics at Huazhong University of Science and Technology in 2009, did his postdoctoral researchin Jeanny Hardy lab at University of Massachusetts, Amherstfrom 2009 to 2010 and Michael Lin lab at Stanford University from 2010 to 2015. He has developedseveral novel fluorescent proteins (FPs) and FP-based biosensors. 1) afar-red bimolecular fluorescence complementation system (BiFC) that works very well under cell physiological conditions, which could be used for monitoring protein-protein interaction in vivo; 2)a GFP-based caspase-3 indicator(CA-GFP) with large dynamic range, which potentially can be used for visualization of cell’s spontaneous apoptosis during embryo and neuron development; 3) a brightest far-red FP, mCardinal, providing a useful tool for optical imaging in vivo; 4)a large Stokes shift orange FP (CyOFP), which can be excited together with GFP using single wavelength, allowing simultaneous visualization of two molecular events under two photon excitation in vivo; and 5) a green FP-red FP based FRET (fluorescence resonance energy transfer) pair (Clover3-mRuby3) with large dynamic range, which is useful for detecting weak or transient biochemical responses in living cells. He has first-authored and co-authored more than 15 journal and conference articles including one Nature Methods, 2 U.S. patents and one invited book chapter. He is a member of Biophysical Society and Protein Society. His current research interests include engineering of novel infra-red FPs for optical imaging and red-absorbing chromoproteins for photoacoustic imaging, engineering of novel large Stokes shift FPs for two photon imaging, improving existing FRET pairs and development of FRET biosensors for kinases, and development of new optogentic tools for perturbing the signaling pathway in living cells.

    储军（个人主页），研究员，博士生导师，2009 年获华中科技大学生物医学工程博士，于2009～2015年在美国麻省大学阿莫思特分校和斯坦福大学进行了博士后研究。开发了具有不同光学性能的荧光蛋白和基于荧光蛋白的探针。主要包括：1）发展了新型的可用于蛋白相互作用监测的远红色荧光互补系统；2）发展了能够用于高灵敏监测细胞凋亡过程中 caspase-3活性的新探针；3）发展了目前最亮的可用于在体荧光成像的远红色荧光蛋白；4）发展了能够和GFP联合可用于双光子双色成像的大 stokes位移的橙色蛋白；5）发展了具有高动态范围的FRET荧光蛋白对。已发表或合作发表了包括Nature Methods在内的15篇期刊和会议论文，申请美国专利2项，发表国际著作章节一篇。现为美国生物物理和蛋白协会会员。

  • Tel：0755-86585221
  • Email：jun.chu@siat.ac.cn
  • Homepage：http://people.ucas.ac.cn/~0052237
    • Liu, Chengbo （刘成波）, PhD, Professor

    Chengbo Liu received both his Ph.D and Bachelor degree from Xi'an Jiaotong University, each in 2012 in Biophysics and 2007 in Biomedical Engineering. During his Ph.D. training, he spent two years doing tissue spectroscopy research at Duke University as a visiting scholar. Now he is a professor at SIAT, working on multi-scale photoacoustic molecular imaging and its translational research. He and his team have published more than 80 journal papers on photoacoustic imaging, and applied for more than 30 patents. He is currently a senior member of OSA, and a member of IEEE and SPIE. He also serves as an editorial board member of Photoacoustic journal, and regular reviewer for more than 30 prestigious journals. Besides academic research, Chengbo enjoys playing soccer.

    刘成波（个人主页），研究员，博士生导师。深圳市海外高层次人才，中科院青促会成员。本科毕业于西安交通大学生物医学工程，博士毕业于西安交通大学生物物理专业，期间在美国杜克大学从事2年研究工作。主要研究方向为多尺度光声分子成像理论方法和技术仪器研究，并开展转移转化工作。目前担任光声成像领域JCR一区期刊Photoacoustics编委，是该期刊现任编委中最年轻一位。主持基金委重大研究计划、中科院仪器研制等重点项目，作为合作方负责人，合作获批基金委重大仪器研制，重点基金项目。已发表高水平论文80多篇，以第一/通讯作者在Light、Advanced Materials等JCR一区期刊发表论文38篇，Web of Science引用1100余次，H-index 26。申请专利38项，授权16项，3个技术专利实现产业转化。担任Nano Letters、Laser Photonics Review等30余个高水平期刊审稿人。

     

  • Tel：0755-86392237
  • Email：cb.liu@siat.ac.cn
  • Homepage：http://people.ucas.ac.cn/~chengbo
    • Gong, Xiaojing（龚小竞） , PhD, Associate Professor

    Xiaojing GONG, Pd.D, Associate Professor,received his B.S. degree in Mechatronics from the Southeast University in 2000, and Ph.D. degree in Fine Instruments and Mechanics from the University of Science and Technology of China in 2007.Since joined the IBHE of SIAT in 2007, Dr.Gongfocuses in the research of Biomedical Optics Imaging, includes Photoacoustic Tomography/Microscopy,Optical Coherence Tomography/Microscopy, Terahertz biomedical imaging, etc.Dr.Gong and his team, for the first time in the world, developed the optical resolution intravascular photoacoustic (OR-IVPA) imaging, high-speed intravascular photoacoustic imaging, full field-of-view photoacoustic endoscopy.And the team is working on the systems improvements, such as multi-modality IVPA, spectroscopic photoacoustic imaging, and the application research on atherosclerosis and tumor diagnosis. He has authored and co-authored more than 20 journal and conference articles, has 3 Chinese patents and one U.S. patent pending.

    龚小竞（个人主页），副研究员，硕士生导师。深圳市高层次人才，生物医学光学与分子影像研究中心副主任，2000年获东南大学机电一体化专业学士，2007年获中国科学技术大学精密仪器与机械专业博士学位。目前主要研究方向为基于光学和声学原理的内窥式成像技术的研发及其临床应用，包括光声成像、光学相干层析成像、超声成像等。龚小竞博士及其团队在国际上率先实现了光学分辨率的血管内光声成像、血管内光声光谱成像、全视场小探头的消化道光声内窥成像等技术。目前正在发展基于光声的多模态血管内/消化道内成像、光声光谱定量分析、光声高速成像等技术，及其在心血管、肿瘤等疾病的诊断中的应用。相关工作在Journal of Biophotonics、Biomedical Optics Express、Journal of Biomedical Optics、 Plos One、Nanoscale等高影响因子期刊发表20余篇，申请国际、中国发明专利14项（已授权5项）。目前主持国家自然科学基金面上项目1项，深圳市基础研究项目2项；作为子课题负责人或核心骨干参与国自然重大仪器专项、科技部重点研发专项、中科院、广东省科技计划、其它纵向、横向课题多项。目前担任国家自然科学基金项目评审、广东省科技专家库专家、深圳市科技评审专家，国际光学工程学会（SPIE）会员，美国光学学会（OSA）会员，中国生物医学工程学会会员，中国研究型医院学会消化内镜分子影像学专业委员会委员, 中国心血管医生创新俱乐部(CCI)会员，以及Photoacoustics、IEEE TMI、ASME、中国激光等多个期刊审稿人。

  • Tel：0755-86392237
  • Email：xj.gong@siat.ac.cn
  • Homepage：http://people.ucas.ac.cn/~xjgong
    • Sun, Qinchao （孙钦超）, PhD, Associate Professor

    Qinchao Sun, Ph.D., Associate Professor at SIAT since 2019. 01. Prior to SIAT, Dr. Sun was a Postdoctoral research fellow at Stanford University and also a visiting scholar at Cornell University. He received Ph.D. in physical chemistry from University of Geneva, Switzerland.  Dr. Sun has published 10+ peer-reviewed papers (JACS, Chemical Science, Coordination Chemistry Review). Currently, Dr. Sun is interested in developing functional materials for solving a few biological problems.  1. Luminescent probes for bioimaging, e.g. cell tracking, neuron activity. 2. Nanomaterials for anti-tumor therapy, e.g. light activated release, photothermal therapy, drug delivery.
     

    孙钦超，副研究员，2019年1月加入SIAT。博士毕业于瑞士日内瓦大学。曾先后在Stanford University 和Cornell 大学做博后研究以及访问学习。已发表peer reviewed 文章10余篇，包括 JACS， Chemical Science，Coordination Chemistry Review。2016年获得国家优秀自费留学生奖。目前研究兴趣在于设计功能材料研究生命之过程。1.光响应探针用于生命过程监测，如细胞追踪，生物成像，神经活动等。2. 纳米材料用于肿瘤的治疗，如光控释放，光热，药物递送等。

  • Tel：0755-86392491
  • Email：qchao.sun@siat.ac.cn
  • Homepage：http://people.ucas.edu.cn/~qchao
    • Li, Hui（李慧），PhD, Associate Professor

    Hui Li, Ph.D., associate professor, received her B.S. degree and Ph.D. degree in Biomedical Engineering from Huazhong University of Science and Technology in 2006 and 2015, respectively. She completed a postdoctoral fellowship at Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences from 2016 to 2018 and is currently an associate professor there. Her research interests focus on biomedical applications of optical microscopy. She has authored and co-authored more than 20 journal articles (including Optics Express, Biomedical Optics Express, eLife, Theranostics, etc.), has directed or is directing 7 scientific projects (including 2 projects supported by the National Natural Science Foundation of China), and has 3 Chinese patents pending. She is a member of Chinese Society of Biomedical Engineering.

    李慧（个人主页），副研究员，硕士生导师，深圳市高层次专业人才“后备级人才”，深圳市南山区“领航人才”。2015年底获得华中科技大学生物医学工程专业博士学位，同年加入中国科学院深圳先进技术研究院生物医学光学与分子影像研究中心。研究方向为生物医学光学显微成像，主要涉及生物组织活体无标记光学显微成像研究，基于光学显微成像的肿瘤识别研究，肿瘤免疫光学显微成像研究，心脑血管疾病的光学显微成像研究等。目前，在《Optics Express》、《Biomedical Optics Express》等光学/生物医学光学领域旗舰期刊以及《eLife》、《Theranostics》等生物/医学领域知名期刊累计发表SCI论文近20篇；申请发明专利6项，获授权3项；主持国家自然科学基金面上项目、青年项目等科研项目7项；参与中科院科研仪器研制项目、国家重点研发计划等重大项目多项。

  • Tel：0755-86392242
  • Email：hui.li@siat.ac.cn
  • Homepage：http://people.ucas.edu.cn/~lihui1
    • Men Yongfan（门涌帆），PhD, Associate Professor

    Dr. Henry Yongfan Men, PhD, Associate Investigator. Graduated as a PhD from Peking University in 2012. From 2012 to 2016, worked as postdoc scholars in Peking University, the University of Notre Dame, and the University of California, Davis, successively. Has been the visiting scholar of University of California, Berkeley. Went back to China and joined SIAT as an associate investigator in 2017. The major research direction is to develop the microfluidic technologies that are of the academic forefronts and highly industrial transferable, especially in robotic intelligence, next generation sequencing, single-cell analysis, phenomics, mass spectroscopy, medical diagnosis. Totally published 14 SCI papers and 8 patents.

    门涌帆（个人主页），副研究员，博士生导师。2012年在北京大学获得博士学位。2012年-2016年，先后在北京大学、美国圣母大学和加州大学戴维斯分校担任博士后研究工作。加州大学伯克利分校访问学者。2017年回国加入中国科学院深圳先进技术研究院，任副研究员。主要研究方向为研发具有科研前沿性和产业化可行性的微流控技术，尤其在机器人智能自动化、下一代基因测序、单细胞分析、表型组学、质谱分析、医疗诊断等关键生物医学工程领域进行重点结合与突破。研究组具有较强的将原创技术进行产业转化的能力。共发表14篇SCI期刊文章，8篇专利。目前主持国家级项目1项，作为核心成员参与广东省创新团队“新型高灵敏度柔性仿生触觉传感技术研发及产业化”项目，主持深圳市基础研究项目2项，参与省级纵向课题及企业横向课题3项。

  • Tel：0755-86392278
  • Email：yf.men@siat.ac.cn
  • Homepage：http://people.ucas.ac.cn/~0064120
    • Lin, Riqiang（林日强），Senior engineer

    Riqiang Lin, senior engineer, received his MA.Sc and B.S. degree in Shenzhen University. Since joined the IBHE of SIAT in 2011, Riqiang Lin focuses in the research of Photoacoustic Imaging, has developed a series of novel photoacoustic system, including optical resolution (OR) and acoustic resolution (AR) photoacoustic microscopy, full field-of-view photoacoustic endoscopy.
    Riqiang Lin and his team, for the first time in the world, got the in vivo PA image of mouse’s dorsal vessels network on OR-PAM, got the in vivo PA/US image of rat’s rectum with full-field of view on PAE. He has authored and co-authored more than 17 journal and conference articles, awarded 15 Chinese invention patents.
     

    林日强，高级工程师。2011年毕业于深圳大学，获机械工程硕士学位。毕业后加入中国科学院深圳先进技术研究院生物医学光学与分子影像研究室，主要从事光声显微系统以及消化道内窥成像系统的研发工作。中国生物医学工程学会会员，中科院优秀青年基金获得者。参与搭建国内第一台反射式光学分辨率光声显微成像系统，2012年首次获得小鼠背部血管网络光声图像。目前从事光声内窥成像的研究，已发表学术论文17篇，其中第一作者SCI学术论文4篇，申请相关中国专利20余项，其中已授权专利18项。

  • Tel：0755-86392242
  • Email：rq.lin@siat.ac.cn
  • Homepage：
    • Chen, Jingqin （陈敬钦）,PhD, Associate Professor

    Jingqin Chen, Ph.D., Associate Professor, Overseas High-caliber Personnel in Shenzhen. He received a master degree in biophysics in 2014 from South China Normal University and a Ph. D in Biochemistry and Molecular Biology from University of Chinese Academy of Sciences in 2020. From 2019 to 2020, he conducted expanded porphyrin synthesis research at The University of Texas at Austin as a visiting scholar. His research interest focus on the synthesis of NIR photoacoustic moleculer imaging probes and their applications on biomedicine. Up to now, he is directing fundings from NSFC and SIAT. Dr. Chen has authored or co-authored 25 peer reviewed publications, of which 15 are first-author papers, such as Advanced Materials, JACS, Advanced Functional Materials, Biomaterials, Light: Science & Applications, Nano-Micro Letters, Biomaterial Science, etc. He has been an inventor of record on 10 issued China Patents.

    陈敬钦，副研究员，深圳市海外高层次人才，2014年7月加入中国科学院深圳先进技术研究院，博士毕业于中国科学院大学。硕士期间获年度“校十佳学术论文奖”，博士期间获国科大“三好学生”奖。2019-2020年在美国德州大学奥斯汀分校Sessler教授课题组从事卟啉光声探针开发研究工作。主要研究方向是开发小分子和二维材料等多功能光声纳米探针并探索其在生物医学领域的应用。近年来，主持和参与包括国自然基金、国家重点研发计划以及省市自然基金在内的多个研究项目；以第一作者身份发表peer reviewed文章15篇，包括Adv. Mater., JACS, Adv. Funct. Mater., Light Sci. Appl., Biomaterials, Nano-Micro Lett.等；申请发明专利10件，授权4件。

  • Tel：0755-86392242
  • Email：jq.chen@siat.ac.cn
  • Homepage：

    • Team members

    Wang，Liang （王亮）, Assistant Professor

    Liang Wang obtained his Ph.D degree in Biomedical Engineering from Wuhan National Laboratory of Optoelectronics at Huazhong University of Science and Technology in 2013. Then he received his postdoctoral training in Khuloud Jaqaman lab at UTSW (Dallas, 2013/10-2014/12) and Jon Cooper lab at Fred Hutch (Seattle, 2014/12-2017/05).
    He has applied fluorescence imaging techniques (such as FRET, FLIM, FRAP, and single molecule imaging) into cell biology research and also developed an optogenetic tool to activate the Dab1 signaling pathway in primary neurons. Currently his interest is to develop biosensors for small metabolites in cells using fluorescent proteins and to develop optogenetic tools to dissect the cellular activities quantitatively.
     

    王亮，博士，助理研究员。2013年获华中科技大学生物医学工程博士学位。2013年10月至2017年5月分别在美国西南医学中心Jaqaman实验室和福瑞德·哈金森癌症研究中心Cooper实验室进行了博士后训练。研究内容主要是将荧光成像技术（比如FRET、FRAP和单分子成像等）应用在细胞生物学的研究中，比如细胞自噬、膜蛋白胞吞胞吐和细胞膜受体运动等。另一方面的研究工作是开发一些光遗传学的工具用以研究细胞信号通路。

  • Tel：0755-86392242
  • Email：liang.wang1@siat.ac.cn
    • Xie，Zhihua（解志华），Assistant Professor

    Zhihua Xie, PHD, Shenzhen institute of advanced technology, Chinese academy of sciences, Institute of biomedical and health engineering, Assistant Professor. Dr. Xie received her Ph.D. degree in Optics from FEMTO-ST institute （CNRS& UBFC）in France in 2016, her research focused on the development of fiber-integrated micro/nano optical elements, with the purpose of single colloidal quantum dot imaging in infrared range or fluorescence collection. In 2012, Zhihua Xie graduated from Changchun institute of optics, mechanics and physics, Chinese academy of sciences with master degree in optics, with the research focused on surface Plasmon nanolithography and the study of fiber-microlens coupling. Xie joined SIAT as a Postdoctor in November, 2016. Her research interests focus on the atherosclerosis plaque imaging based on intravascular photoacoustic technique. Dr .Xie has published four SCI papers as the first author, including Nanoletters, Optics Letters, etc.
     

    解志华，博士，中国科学院深圳先进技术研究院，生物医学光学与分子影像研究室，助理研究员。2016年毕业于法国FEMTO-ST研究所（法国科学院，勃艮第-弗郎士-孔泰大学），获光学博士学位。主要从事光纤集成微纳元件的开发，用于实现单量子点成像或荧光收集。2012年毕业于中国科学院长春光机所，获光学硕士学位，主要从事表面等离子体光刻，光纤微透镜耦合光学设计方面的研究。2016年10月加入中国科学院深圳先进技术研究院，目前主要从事动脉粥样硬化血管内光声成像等工作。并以第一作者身份发表SCI论文四篇，包括Nanoletters、Optics Letters等。 

  • Tel：0755-86392242
  • Email：zh.xie@siat.ac.cn
    • Liao，Jiuling（廖九零）,Assistant Professor

    Jiuling Liao received his B.S. degree in Photoelectric Information Engineering from Nanjing University of Science and Technology in 2012, and Ph.D. degree in Optical Engineering from Nanjing University of Science and Technology in 2017. He has first-authored and co-authored more than 10 journal and conference articles, 2 Chinese patents. Dr. Liao joined SIAT as a Postdoctor in July, 2017. His research interest focuses on the application of multimodal microscopy.
     

    廖九零，助理研究员，2012年获南京理工大学光电信息工程专业学士学位，2017年获南京理工大学光学工程专业工学博士学位。已发表或合作发表期刊及会议论文10余篇，发明专利授权2项。同年7月加入深圳先进技术研究院，任博士后，并于2019年6月出站留院，任助理研究员。目前研究方向为多模态显微成像。

  • Tel：0755-86392242
  • Email：jl.liao@siat.ac.cn
    • Deng，Mengying（邓梦颖），Assistant Professor

    Mengying Deng, PHD, Shenzhen institute of advanced technology, Chinese academy of sciences, Institute of biomedical and health engineering, POSTDC. Dr. Deng received her Ph.D. degree in Sun Yet-sen University in 2016, her research focused on the biological function of T3SS secretory effectors Rip I and RipAK of the bacteria Ralstonia solanacearum with two SCI papers published. In 2011, Mengying Deng graduated from Nanchang University with master degree, with the research focused on ISSR genetic diversity of four major Chinese carps in Poyang Lake and its original rivers. Deng joined SIAT as a Postdoctor in July, 2017. Her research interests focus on the screening of red fluorescent proteins and its application in neurobiology.
     

    邓梦颖，助理研究员。2015年毕业于中山大学生命科学学院，获微生物学博士学位。主要从事茄科劳尔氏菌三型分泌系统效应蛋白Rip I和RipAK功能研究，并发表两篇SCI论文。2011年毕业于南昌大学，获动物学硕士学位，主要从事鄱阳湖水系四大家鱼ISSR遗传多样性研究。2017年7月加入中国科学院深圳先进技术研究院，目前主要从事红色荧光蛋白的筛选及其在神经生物学方面的应用研究。

  • Tel：0755-86392242
  • Email：my.deng@siat.ac.cn
    • Zhang，Chen（章辰）， Assistant Professor

    Chen Zhang, PHD, Shenzhen institute of advanced technology, Chinese academy of sciences, Institute of biomedical and health engineering, assistant professor. Dr. Zhang received her Ph.D. degree in Optical Engineering from Sichuan University in 2018. Dr. Zhang has first-authored and co-authored more than ten journal and conference articles, including Optics and Lasers in Engineering and Optics Express, and two Chinese patents. Zhang joined SIAT as a Post-doctor in July, 2018. Her research interests focus on development and application of multi-scale photoacoustic microscopy imaging system.
     

    章辰，助理研究员。2018年毕业于四川大学，获光学工程博士学位。已发表或合作发表期刊及会议论文10余篇，包括Optics and Lasers in Engineering、 Optics Express等，已授权国家发明专利2项。2018年7月加入中国科学院深圳先进技术研究院，主要研究方向是跨尺度光声显微成像系统的开发与应用。

  • Tel：0755-86392242
  • Email：chen.zhang@siat.ac.cn
    • Zhang，Jinke（张进珂），Assistant Professor

    Jinke Zhang, Assistant Professor, Chinese Academy of Sciences, Shenzhen Institute of Advanced Technology, Institute of Biomedical and Health Engineering. Dr. Zhang received his Ph.D. degree in Electrical Engineering and Electronics, University of Liverpool in UK with the research focused on the development of optical coherence tomography systems and their applications in pharmaceutical industry and medical diagnosis. Dr. Zhang joined SIAT as a postdoctor in Feb, 2018. His research interests focus on the photoacoustic endoscopy in gastrointestinal tract. Dr. Zhang has published one SCI paper as the first author and one conference paper.

     

    张进珂，博士，助理研究员。2018年毕业于英国利物浦大学，电气工程及电子系，获得工学博士学位。主要从事相干光学层析成像系统的开发和实现用于医药行业的三维微米级分辨率无损检测。2018年2月加入中国科学院深圳先进技术研究院，目前主要从事消化道内光声内窥成像等工作。以第一作者身份发表SCI论文1篇，会议论文1篇。

  • Tel：0755-86392242
  • Email：jk.zhang@siat.ac.cn
    • Gao, Rongkang（高蓉康），Assistant Professor

    Gao, Rongkang, PhD, Shenzhen institute of advanced technology, Chinese academy of sciences, Institute of biomedical and health engineering, Assistant Professor. Dr. Gao received her Ph.D. degree in Mechanical Engineering from the University of New South Wales, Australia, 2018. Her Ph.D. thesis explored a non-intrusive measurement technique using the absorption spectroscopy and hollow core photonic crystal fiber for the investigation of micro-fluid dynamics. Dr. Gao has published 6 papers including journal articles and conference papers, and she joined SIAT as a Post-doc fellow in November, 2018. Dr. Gao’s research interests focus on the development and application of photoacoustic spectroscopy, and photoacoustic technique applied to evaluate and optimize the photodynamic therapy.

     

    高蓉康，博士，助理研究员。2018年毕业于澳大利亚新南威尔士大学，获机械工程博士学位，博士期间研究是基于光谱吸收技术和空心光子晶体纤维，开发了一种非侵入式的光谱传感器，用于微管流动力学研究。已发表期刊论文及会议论文6篇，包括Experiments in fluids、Experimental Thermal and Fluid Science等。2018年11月加入中国科学院深圳先进技术研究院，主要研究方向是光声光谱技术开发与应用，以及光谱技术用于评估和优化光动力治疗的研究。
     

  • Tel：0755-86585207
  • Email：rk.gao@siat.ac.cn
    • REN, Yaguang（任亚光）, Assistant Professor

    Yaguang REN, PhD,Assistant Professor. Shenzhen institute of advanced technology (SIAT), Chinese academy of sciences, Institute of biomedical and health engineering. Dr. REN received her Master degree in Optical Engineering from Tianjin University in 2013, her research focused on the development of white light interference system for ultra-high precision detection and optical fiber sensing. In 2014, she went to the Hong Kong University of Science and Technology, and pursued her Doctor degree in the Division of Biomedical Engineering, mainly did NMR image reconstruction related studies. She graduated in 2018 and then entered the Division of Life Science and worked as a short time scholar visitor to study the single molecule detection using the Total-internal reflection Fluorescence Resonance Energy Transfer system. She joined SIAT in Jan, 2019 as a Post-doctor. Her research interests focus on theoretical and method study on multi-scale Low-Rank Sparse reconstruction of heart photo-acoustic imaging.
     

    任亚光，博士，助理研究员。2013年获天津大学，光学工程专业硕士学位。硕士期间主要从事基于白光干涉的高精度光学检测和光纤传感研究。2014年进入香港科技大学生物医学部开始博士学习，主要从事核磁共振图像重建的研究工作。2018年博士获得生物工程学博士学位，随后又进入生命科学部门做短期访问学者，主要进行基于全反射-荧光共振能量转移的单分子检测研究。2019年1月加入中国科学院深圳先进技术研究院，主要从事多尺度低秩-稀疏心脏光声图像重建理论和方法研究。
     

  • Tel：0755-86585207
  • Email：yg.ren@siat.ac.cn
    • LI,Wen（李雯）， Assistant Professor

    Wen LI, Ph.D. Shenzhen institute of advanced technology (SIAT), Chinese academy of sciences (CAS), Institute of biomedical and health engineering, Assistant professor. Dr. Li received her Ph.D degree in The Chinese University of Hong Kong (CUHK), 2017. Her study focused on the mechanism of FE65 and its integrating proteins in the regulation of neurodevelopment. After graduation, she worked at CUHK as a Research Assistant till June 2018. Then, she joined SIAT in July 2018 as a postdoctoral fellow. Currently, she is focusing on the study of cell-cell communication on microfluidic chip, and microfluidics combined with HDX-MS for characterization of protein structure.


    李雯，博士，助理研究员。2017年毕业于香港中文大学，获得生物化学博士学位。博士期间主要从事于FE65和其结合蛋白在神经发育中的调控机制。毕业后继续在香港中文大学科研助理职位工作。2018年7月加入中国科学院深圳先进技术研究院，主要研究微流芯片上的细胞通讯，以及基于微流芯片-氢氘交换质谱的蛋白构象解析。

  • Tel：
  • Email：wen.li1@siat.ac.cn
    • Liu，Wenfeng（刘文峰）, Assistant Professor

    Wenfeng LIU, PhD, Assistant Professor, Shenzhen institute of advanced technology (SIAT), Chinese academy of sciences (CAS), Institute of biomedical and health engineering, Postdoc fellow. Dr. Liu received her Ph.D degree in “sciences de la vie et de la santé” from “Université Paris-Sud”, France, Sep 2018. The major project of her Ph.D thesis is exploring the regulation network of regulatory RNA, also named sRNA (small RNA) in Staphylococcus aureus, which is implicated in antibiotics resistance. Dr. Liu has published two papers in Frontiers in Microbiology and Methods, respectively. She joined SIAT as a Post-doc fellow in January, 2019. Dr. Liu is concentrating on the optimization and application of fluorescent probe in mammal.

     

    刘文峰，博士，助理研究员。2018年9月毕业于法国巴黎第十一大学，获得生命与健康科学博士学位，博士期间主要研究调控性RNA（又称“小RNA”）在致病性金黄色葡萄球菌耐药性中的调节作用和调控网络。已分别在Frontiers in Microbiology 和Methods发表学术论文两篇。2019年1月加入中国科学院深圳先进技术研究院，主要研究方向是荧光探针在哺乳动物细胞内的优化和应用。
     

  • Tel：0755-86585207
  • Email：wf.liu@siat.ac.cn
    • Chang, Zong （常宗）,Postdoctoral

    Zong CHANG, PhD, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences Institute of Biomedical and Health Engineering. Dr. Chang received his Ph.D. degree in Université Paris-Sud, France in 2018, focusing on the syntheses of functionalized complex cyclobutane derivatives via photochemical approaches. He has published 6 papers (Angewandte Chemie International Edition, Chemical Communications, Organic Letters, and Journal of Organic Chemistry). He joined SIAT as a postdoc fellow in March 2019, and his research interests focus on the syntheses of fluorescent probes/nanomaterials and their applications in bioimaging and anti-tumor therapy.
     

    常宗，博士后。2018年毕业于法国巴黎第十一大学，获得有机化学博士学位，博士期间从事光化学合成官能团化的复杂环丁烷结构的研究。目前已发表学术论文6篇，包括Angewandte Chemie International Edition, Chemical Communications, Organic Letters, and Journal of Organic Chemistry。2019年3月加入中国科学院深圳先进技术研究院孙钦超博士课题组，从事荧光探针和纳米材料合成及应用方面的研究。
     

  • Tel：0755-86585207
  • Email：zong.chang@siat.ac.cn
    • Chen, Tao（陈涛），Postdoctoral

    Chen Tao, PhD, Shenzhen institute of advanced technology, Chinese academy of sciences, Institute of biomedical and health engineering, Postdoc fellow. Dr. Chen received her Ph.D. degree in Condensed Matter Physics from Institute of High Energy Physics, Chinese academy of Sciences in 2019. He has focused on spectral methodology of synchrotron radiation during his doctoral research and has first-authored and co-authored seven journal articles. Chen joined SIAT as a Post-doctor in July, 2019. His research interests focus on the development and application of ring-shaped detector array photoacoustic computed tomography.

    陈涛，博士后，2019年6月毕业于中国科学院高能物理研究所，获理学博士学位，博士期间研究方向是同步辐射方法技术与应用，具体从事光谱方法学的开发和应用研究,已发表或合作发表期刊论文7篇。2019年7月加入深圳先进技术研究院，生物医学光学与分子影像研究室做博士后。主要研究方向是环形阵列光声计算层析成像技术的开发与应用，具体负责系统的算法改进和应用探索。

  • Tel：0755-86585207
  • Email：tao.chen1@siat.ac.cn
    • Yu, Haixia（于海霞），Postdoctoral

    Haixia Yu, PhD, Shenzhen Instiute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Institute of Bimedical and Health Engineering. Dr. Yu received her doctor degree in organic degree Beijing Institute of Technology in 2019 and majored in organic small molecules with aggregation-induced emission property for the applications in chemosensor, bioimaging and stimuli-responsive materials. She has published three Chinese patents and two papers ( Mater. Chem. Front. and J. Mater. Chem. C). She joined SIAT as a postdoc fellow in August 2019, and she is mainly engaged in the research on the development of near-infrared fluorescent materials for bioimaging in vivo.

    于海霞，博士后，2019年获得北京理工大学有机化学博士学位，博士期间主要从事具有聚集诱导发光性质的有机小分子的合成及在化学传感、生物成像和刺激响应方面的应用研究。目前已发表中国专利三篇和学术论文两篇（Mater. Chem. Front. 和 J. Mater. Chem. C）。2019年8月加入中国科学院深圳先进技术研究院，从事近红外荧光材料的开发和活体成像应用研究的科研项目。

  • Tel：0755-86585207
  • Email：hx.yu@siat.ac.cn
    • Guan, Xinmeng（关欣萌），Postdoctoral

    Xinmeng Guan，PhD. Shenzhen institute of advanced technology (SIAT), Chinese academy of sciences (CAS), Institute of biomedical and health engineering, Postdoc fellow. Dr. Guan received her Ph.D degree in Wuhan institute of Virology (WIV), Chinese academy of sciences (CAS), focusing of the mechanism of HSV-2 evading innate immune signaling pathway. In 2017, She went to St. George’s, University of London, funded by Newton Fund Scholarship and focused on using plat expression system expressing vaccine candidate. She joined SIAT in August, 2019 as a postdoc fellow. She is focusing on the development of fluorescent probe.

    关欣萌，博士后。2019年6月毕业于中国科学院武汉病毒研究所，获理学博士学位。博士期间主要从事单纯疱疹病毒II型逃逸天然免疫信号通路的机制的研究。2017年受牛顿奖学金资助在伦敦大学圣乔治医学院进行联合培养，进行利用植物表达系统表达疫苗候选物的研究。2019年8月加入中国科学院深圳先进技术研究院，目前主要从事荧光探针的研究。

  • Tel：0755-86585207
  • Email：xm.guan@siat.ac.cn
    • Ye, Shiwei（叶世蔚），Postdoctoral

    Shiwei Ye, PhD, Shenzhen institute of advanced technology, Chinese academy of sciences, Institute of biomedical and health engineering, POSTDC. Dr. Ye received his Ph.D. degree in Advanced Interdisciplinary Studies from The University of Tokyo. The main content of his Ph.D. work is to develop an optical depth-measurement method of functional microstructures beyond the diffraction limit. He has first-authored and co-authored more than 15 journal and conference articles, including CIRP and Precision Engineering, and 2 Chinese patents. He joined SIAT as a Post-doctor in September, 2019. His research interests focus on large field-of view two-photon microscope with high spatial and temporal resolution.

    叶世蔚，博士后。2019年9月毕业于日本东京大学，获工学博士学位，博士期间主要的研究方向是超分辨率成像，近场光学及精密测量技术。已发表或合作发表期刊及会议论文15篇，包括CIRP和Precision Engineering，授权国家发明专利2项。2019年9月加入中国科学院深圳先进技术研究院任博士后，目前主要从事高分辨率的大视场双光子显微成像技术。

  • Tel：0755-86585207
  • Email：shiwei.ye@siat.ac.cn
    • Bu,Wenting （布文婷），Postdoctoral

    Wenting BU, Ph.D. Shenzhen institute of advanced technology (SIAT), Chinese academy of sciences (CAS), Institute of biomedical and health engineering, Postdoc fellow. Dr. Bu received her Ph.D degree in Nanyang Technological University (NTU) in Singapore, 2018. Her major was the structural and functional study of kindlins in integrin activation. After graduation, she continued doing research at NTU as a research fellow till February 2020. She joined SIAT in March 2020 as a postdoc fellow. She is focusing on the mechanism study of Wnt signaling using microfluidic.


    布文婷，博士后。2018年6月毕业于新加坡南洋理工大学，获理学博士学位。博士期间主要从事对kindlin蛋白在整合素蛋白激活中的结构和功能研究。毕业后继续在NTU以博士后身份进行科研工作。2020年3月加入中国科学院深圳先进技术研究院，主要研究方向为利用微流控技术探究Wnt信号通路机制。

  • Tel：
  • Email：wt.bu@siat.ac.cn
    • Kong, Weijun（孔维俊）， Postdoctoral

    Weijun Kong, Ph.D. Shenzhen institute of advanced technology (SIAT), Chinese academy of sciences (CAS), Institute of biomedical and health engineering, Postdoc fellow. Dr. Kong received his Ph.D. degree in University of Science and Technology of China in 2019, focusing on the analytical application of chemiluminescence functionalized magnetic microbeads and study on single particle chemiluminescence imaging. He has published 10 papers (Chemical Science, Analytical Chemistry，Chemical Communications and Biosensors & Bioelectronics). He joined SIAT as a postdoc fellow in March 2020, and his research interests focus on microfluidic chip based on alternating current spray.


    孔维俊，博士后。2019年6月毕业于中国科学技术大学，获分析化学博士学位。博士期间主要研究方向是单粒子化学发光成像技术和化学发光功能化材料的开发及其生化传感应用。已发表或合作发表期刊论文10篇，包括Chemical Science，Analytical Chemistry，Chemical Communications和Biosensors & Bioelectronics。2020年3月加入中国科学院深圳先进技术研究院，主要从事基于交流电喷雾的微流控芯片研究。

  • Tel：
  • Email：wj.kong@siat.ac.cn
    • Yang, Fangfang（杨方方），Postdoctoral

    Fangfang Yang, PHD, Shenzhen institute of advanced technology, Chinese academy of sciences, Institute of biomedical and health engineering, POSTDC. Dr. Yang received her Ph.D. degree in optics from South China Normal University in 2019. Her research focused on fluorescence imaging, fluorescence resonance energy transfer (FRET) technology and its application to study the mechanism of apoptosis. Dr. Yang has first-authored and co-first authored three SCI papers, including Cellular and Molecular Life Sciences, Applied Physics Letters, etc. Yang joined SIAT as a Post-doctor in June, 2020. Her research interests focus on screening of red fluorescence protein, the optimization of green-red FRET and the application of acoustic genetic biology.


    杨方方，博士后。2019年12月毕业于华南师范大学，获光学博士学位，博士期间主要的研究方向是荧光成像，荧光共振能量转移（FRET）技术及其应用于研究凋亡调控机制。以第一作者或并列第一作者身份发表SCI论文三篇，包括Cellular and Molecular Life Sciences，Applied Physics Letters等。2020年6月加入中国科学院深圳先进技术研究院任博士后，目前主要从事红色荧光蛋白的筛选、绿红FRET对的优化及声遗传生物学方面的应用。

  • Tel：
  • Email：ff.yang@siat.ac.cn
    • Xu, Zhiqiang （徐智强）, Postdoctoral

    Zhiqiang. Xu, PhD, Shenzhen institute of advanced technology, Chinese academy of science, Institute of biomedical and health engineering, Postdoc fellow. Dr. Xu obtained his PhD degree in Information and Communication Engineering from Wuhan University of Technology in 2020. He joined the photoacoustic imaging lab in University of Virginia during his PhD research. He has published 4 SCI papers and 3 conference papers as the first or communication author. Dr. Xu joined SIAT as a Post-doctor in July, 2020. His research interests focus on the development and application of multi-scale, fast photoacoustic microscopy system.


    徐智强，博士后。2020年毕业于武汉理工大学，获信息与通信工程博士学位。博士期间曾前往美国弗吉尼亚大学进行联合培养。以第一作者或通讯作者身份发表SCI论文4篇，会议论文3篇。2020年7月加入中国科学院深圳先进技术研究院，主要研究方向是跨尺度、快速光声显微成像技术开发及其应用。
     

  • Tel：
  • Email：zq.xu@siat.ac.cn
    • Niu，Chaojun（牛超君），Postdoctoral

    Chaojun Niu, PhD, Shenzhen institute of advanced technology, Chinese academy of science, Institute of biomedical and health engineering, Postdoc fellow. Dr. Niu obtained her PhD degree in Optics from Xidian University in 2019. She joined the Intelligent Optics Lab in University of Dayton during her PhD research. She has published 4 journal papers and 4 conference papers as the first author. Her research focused on laser beam propagating through atmospheric/oceanic turbulence and adaptive optics. Dr. Niu joined SIAT as a Post-doctor in May, 2020. Her research interests focus on the photoacoustic endoscope system based on adaptive optics.

    牛超君，博士后。 2019年毕业于西安电子科技大学，获光学博士学位。博士期间曾前往美国代顿大学先进光学实验室进行联合培养。以第一作者身份发表期刊四篇、会议论文四篇。主要从事大气/海洋湍流传输特性及自适应光学等方面的研究。2020年5月加入中国科学院深圳先进技术研究院，目前主要从事基于自适应光学的光声内窥成像等工作。

  • Tel：
  • Email：cj.niu@siat.ac.cn
    • Gao, Yufeng （高玉峰）, Research Assistant

    Yufeng Gao obtained my master's degree at Harbin Institute of Technology in Jan, 2017. His current research interest focuses on research on wavefront correction of two photo microscopy based on adaptive optics. 

    高玉峰, 硕士，研究助理。2017年毕业于哈尔滨工业大学深圳研究生院，获得物电电子学硕士学位，目前研究方向：基于自适应光学双光子显微波前矫正研究。

  • Tel：0755-86392242
  • Email：yf.gao@siat.ac.cn
    • Yu, Jia（余佳），Research Assistant

    Jia Yu received his Master’s degree in Opto-electronic and Photonic Technology from Tianjin University in January 2017. His current research interest focuses on Re-scan Confocal Microscopy imaging technology.
    余佳，硕士，研究助理。2017年1月毕业于天津大学，获光电子与光子学技术硕士学位。目前主要研究方向为重复扫描共聚焦显微成像技术。

  • Tel：0755-86392242
  • Email：jia.yu@siat.ac.cn
    • Wu, Ting（吴婷），Research Assistant

    Wu Ting received her Master’s degree of Optical Engineering from Beijing University of Technology in 2017.During the Master’s degree, she was engaged in the research about diode pumped high-power solid-state lasers, mainly focusing on a kind of self-adaptive, self-Q-switching laser with single frequency output based on gain grating and design of high energy planar waveguide lasers, and got two papers published in “Optics and Laser technology” and “Infrared and Laser Engineering”. Currently, her main research orientations center on the two-photon microscope used in vivo imaging, concentrating on exploring new ways to improve the technical performance and applications of this imaging system.

    吴婷，硕士，研究助理，2017年毕业于北京工业大学光学工程专业，获硕士学位。硕士主要研究方向为高功率全固态自调Q脉冲激光器和高功率平面波导连续激光器研究。在Optics and Laser technology” 和 “红外与固体激光工程”发表两篇论文。目前主要研究方向为双光子光学显微成像系统及其应用。

  • Tel：0755-86392242
  • Email：ting.wu@siat.ac.cn
    • Liu, Liangjian（刘良检），Research Assistant

    Liu Liangjian received his Master’s degree of Mechanical engineering from Harbin Institute of Technology in 2015. His current research focuses  on Photoacoustic  microscopy system design and application.

    刘良检，硕士，助理工程师。2015年毕业于哈尔滨工业大学机械工程专业，获硕士学位。目前主要研究方向为光声成像系统的设计与应用。

  • Tel：0755-86585207
  • Email：lj.liu@siat.ac.cn
    • Liu, Lina（刘丽娜）, Research Assistant

    Liu Lina received her Master’s degree of Optics from Shenzhen University in 2019. Her current research interest focuses on optical microscopy imaging and tissue optical transparency technology research.

    刘丽娜，硕士，研究助理。2019年毕业于深圳大学，获光学硕士学位。目前主要研究方向为光学显微成像及组织光透明技术研究。

  • Tel：0755-86585207
  • Email：lina.liu@siat.ac.cn
    • Chen, Ningbo（陈宁波），Research Assistant

    Ningbo Chen received his Master’s degree of Mechanical Engineering from Guangzhou University in 2019. His research focuses on photoacoustic microscopy imaging systems and its biomedical applications. He has authored and co-authored 6 journal articles, including Advanced Materials、Journal of Biophotonics、Photoacoustics .etc, and 2 Chinese patents.

    陈宁波，硕士，研究助理。2019年毕业于广州大学机械工程专业，获硕士学位。目前主要从事光声显微成像系统的设计及其生物医学应用研究，已发表或合作发表期刊论文6篇，包括Advanced Materials、Journal of Biophotonics、Photoacoustics等，申请中国发明专利2项。

  • Tel：0755-86392491
  • Email：nb.chen@siat.ac.cn

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