On January 7, 2025, Professor Nie Liming from Xiamen University was invited by Researcher Liu Chengbo of the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, to visit the Photoacoustic Imaging Laboratory. He delivered an academic lecture titled "Optical Imaging and Its Biomedical Applications."

Over the past decades, photoacoustic imaging has seen significant advancements in its principles and technologies. However, translating these technologies into practical medical research applications remains a challenge.

In his lecture, Professor Nie shared the latest developments from his research group in photoacoustic molecular imaging, including photoacoustic tomography and photoacoustic microscopy. He also discussed the application of existing photoacoustic equipment and algorithms in the biomedical field. The presentation covered topics such as hepatic sinusoids permeability imaging, renal metabolic imaging, and the use of photoacoustic imaging to evaluate lipid changes induced by drugs promoting white adipose tissue browning.

Professor Nie engaged in discussions with faculty and students at the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

Professor Lai and Researcher Chengbo Liu engaged in discussions within the laboratory

Personal Profile：

Professor Nie Liming, a distinguished scholar at Xiamen University, has been honored with titles such as the National Science Fund for Distinguished Young Scholars, one of the inaugural Nanchang Young Top Talents, Zhejiang Province's Distinguished Expert, and Fujian Province's Outstanding Youth and High-Level Talent. His research focuses on molecular imaging and the integration of medical engineering, leading to significant advancements in photoacoustic microscopy through improved optical and acoustic confocal efficiency. He introduced the concept of the photon recycler and developed multimodal probes based on ultra-sensitive photoacoustic detection. His team overcame challenges related to deep tissue detection sensitivity and elucidated the role of local magnetic field inhomogeneity as a key factor in T2-weighted imaging enhancement, refining MRI contrast mechanisms. By achieving precise identification of lesion boundaries across molecular, microvascular, and tissue scales, they addressed issues of tumor boundary blurring. As corresponding or first author, Professor Nie has published over 50 papers in journals such as Nature Communications, Journal of Nuclear Medicine, Angewandte Chemie, and Cancer Letters, which have been cited over 4,000 times. He has led projects funded by the National Natural Science Foundation, the Ministry of Science and Technology's 863 Program, and university grants, and has participated as a core member in a Ministry of Science and Technology 973 Program project. He holds patents in both the U.S. and China and serves as a reviewer for international journals including IEEE Transactions on Medical Imaging, Biomedical Optics Express, Advanced Materials, and Theranostics.