刘成波 博士，研究员、博士生导师

刘成波，博士，研究员，博士生导师，国家优青。担任光声成像JCR一区期刊Photoacoustics编委，入选SPIE/OSA/IEEE Senior Member。2007年本科毕业于西安交通大学生物医学工程专业，2012年博士毕业于西安交通大学生物物理专业，2009-2011年在美国杜克大学进行联合培养。主要研究方向为光声成像技术与仪器，并开展转移转化工作。主持科技部重点研发计划（2项）、基金委重大研究计划（2项）、中科院仪器研制等项目，作为合作方负责人，合作获批基金委重大仪器研制，重点基金项目。已发表高水平SCI论文100多篇，以第一/通讯作者在PNAS等期刊发表论文50多篇，Web of Science引用3000余次，H-index 35，授权发明专利20余项。担任Nature BME等多个高水平期刊审稿人。

陈敬钦 博士，副研究员、硕士生导师

陈敬钦，博士，副研究员，硕士生导师，深圳市海外高层次人才，中科院青促会会员。2014年7月加入中国科学院深圳先进技术研究院，博士毕业于中国科学院大学生物化学与分子生物学专业。2019-2020年在美国德州大学奥斯汀分校Sessler院士课题组从事分子探针合成工作。主要研究方向是炎症微环境的靶向调控与分子诊疗研究。近年来，主持国自然青年、面上，中科院青促会人才项目等，参与包括国家重点研发计划以及省市自然基金在内的多个研究项目；目前已发表高水平SCI论文40余篇，以第一/通讯作者在PNAS、JACS、AM等期刊发表论文18篇，google scholar引用1600余次，H-index 21，授权发明专利5件。

高蓉康 博士，副研究员、硕士生导师

高蓉康，博士，副研究员，深圳市海外高层次人才，2018年毕业于澳大利亚新南威尔士大学，获机械工程博士学位。2018年11月加入中国科学院深圳先进技术研究院，主要研究方向为光声成像理论方法、高分辨率高灵敏度光声技术开发与应用、以及光声成像算法研究工作等。已在国际知名学术期刊发表高水平SCI期刊论文16篇，其中第一作者10篇，包括Laser & Photonics Reviews, Photoacoustics, Analytical Chemistry, European Journal of Nuclear Medicine and Molecular Imaging, Physics of Fluids等。申请发明专利6项。近年来，主持国自然基金1项、深圳市基础研究面上基金1项、中国博士后面上基金1项，同时作为核心成员参与包括国家重点研发计划以及基金委重大研究计划在内的多个研究项目。担任Photoacoustics等多个期刊审稿人。

任亚光 博士，助理研究员

任亚光，博士，助理研究员。2013年获天津大学，光学工程专业硕士学位。硕士期间主要从事基于白光干涉的高精度光学检测和光纤传感研究。2014年进入香港科技大学生物医学部开始博士学习，主要从事核磁共振图像重建的研究工作。2018年博士获得生物工程学博士学位，随后又进入生命科学部门做短期访问学者，主要进行基于全反射-荧光共振能量转移的单分子检测研究。2019年1月加入中国科学院深圳先进技术研究院，主要从事多尺度低秩-稀疏心脏光声图像重建理论和方法研究。

徐智强 博士，助理研究员

徐智强，博士，助理研究员。2020年毕业于武汉理工大学，获信息与通信工程博士学位。博士期间曾前往美国弗吉尼亚大学进行联合培养。以第一作者或通讯作者身份发表SCI论文4篇，会议论文3篇。2020年7月加入中国科学院深圳先进技术研究院，主要研究方向是跨尺度、快速光声显微成像技术开发及其应用。

陈宁波 在职博士生，助理研究员

陈宁波，硕士，助理研究员。2019年毕业于广州大学机械工程专业，获硕士学位。目前主要从事光声显微成像系统的设计及其生物医学应用研究，已发表或合作发表期刊论文6篇，包括Advanced Materials、Journal of Biophotonics、Photoacoustics等，申请中国发明专利2项。

刘良检，在读博士生

刘良检，博士在读。本硕毕业于哈尔滨工业大学。现在主要从事光声设备研制工作，共发表一作SCI文章5篇。

雷天成，在读硕士生

雷天成，硕士在读。2021年毕业于南京航空航天大学，获生物医学工程学士学位。同年被录取加入中国科学院深圳先进技术研究院，已发表期刊论文一篇，主要从事光声显微成像技术的研究。

吴志峰，在读硕士生

吴志峰，硕士在读。2022年毕业于中国矿业大学，获机械工程学士学位。硕士期间与南方科技大学进行联合培养。目前主要从事光声显微成像系统的设计及其生物医学应用的研究。

吴涛峰，在读本科生

吴涛峰，本科在读，就读于广州医科大学生物医学工程专业。2022年9月预录取为中国科学院深圳先进技术研究院硕士研究生，主要研究方向为光声显微成像技术。

Lai，Zhenjie（赖圳杰），深圳大学客座硕士研究生

赖圳杰，深圳大学客座硕士研究生，机械工程专业，主要研究方向为基于光声成像的新型生物医学成像系统。

光声新理论新方法

        光声效应的产生涉及多个物理机制，包括光热转换、热传导、热弹性膨胀、压力波传播、温度场和声场分布等。对这些物理机制和现象的有效利用和巧妙操控，可以实现光声温度提取、超分辨率成像、超对比度成像、光声引导光学聚焦、血液流速测量、以及单波长功能成像等，极大地拓展了光声成像技术的应用范围。与此同时，对多种成像算法的有效探索（例如，虚拟点合成孔径算法、反卷积算法、正向投影、背向投影重建算法、声速补偿、滤波反投影等），有利于实现超分辨和大深度光声三维成像，使光声成像‘看的更清楚’和‘看的更深入’。目前本实验室从物理机制和成像算法两方面出发，开展了光声新理论新方法研究，在提高光声成像性能的同时，积极拓宽光声效应和技术的应用维度和范围，推动光声技术进一步发展。

光声显微成像

光声显微成像技术可通过血红蛋白等内源性吸收体实现活体生物组织的无标记、高分辨结构和功能成像，现已在神经学、眼科学、肿瘤学、皮肤学多个生物医学领域得到应用。本实验室致力于高性能光声显微成像研究，从设备（高速、跨尺度、多模态等）、算法（信号去噪、图像增强、血管定量等）、应用（神经血管耦联、肿瘤微环境等）三个层面推动该技术的发展。

光声计算层析成像

光声计算层析成像(PACT)具有高安全性、高分辨率、大成像深度以及实时成像等优点，能够提供生物组织结构、功能、代谢等方面的重要信息，被证明在生物医学多个领域具有重要的应用价值。本实验室致力于研发新型光声计算层析成像仪器及应用算法，目前已开发专注于人体外周血管光声成像和小动物光声成像两套系统，有望在生物医学成像领域中取得更大突破，为相关疾病的诊断、治疗和疗效评估提供丰富而有价值的信息。

2023

[93] Chang, Zong; Liu, Liangjian; Zhai, Jingying; Liu, Chenchen; Wang, Xiao; Liu, Chengbo*; Xie, Xiaojiang*; Sun, Qinchao*, “Molecular Electronic Coupling-Induced Photoacoustics for NIR-I/II Duplex in Vivo Imaging”, Chemistry of materials, 35( 3): 1335-1344. (SCI, IF=10.508)

[92] Lan, Ruodan; Lv, Jianxun; Gao, Duyang; Hu, Dehong; Liu, Chunchen; Jia, Jie; Zheng, Hairong; Liu, Chengbo*; Zhao, Ping*; Sheng, Zonghai*, “Folate receptor-targeted nir-ii dual-model nanoprobes for multiscale visualization of macrophages in rheumatoid arthritis”, Advanced functional materials, Accepted, DOI: 10.1002/adfm.202300342, 2023. (SCI, IF=19.924)

2022

[91]Rongkang Gao, Qiang Xue, Yaguang Ren, Hai Zhang, Liang Song, Chengbo Liu*, "Achieving depth-independent lateral resolution in AR-PAM using the synthetic-aperture focusing technique" , Photoacoustics, 26:100328, 2022. (SCI, IF=8.484)

[90] [Rongkang Gao, Feng Liu]1, Wenfeng Liu, Silue Zeng, Jingqin Chen, Ruru Gao, Liang Wang, Chihua Fang, Liang Song, Adam C. Sedgwick, Jonathan L. Sessler*, Jun Chu*, Fei Yan*, Chengbo Liu*, "Background-suppressed tumor-targeted photoacoustic imaging using bacterial carriers" , PNAS，119(8):e2121982119, 2022. (SCI, IF=12.779)

[89]Huangxuan Zhao, Jia Huang, Qiang Zhou, Ningbo Chen, Liangjian Liu, Xinggang Wang, Tao Wang, Leqing Chen, Chengbo Liu*, Chuansheng Zheng*, Fan Yang*, "Deep Learning-Based Optical-Resolution Photoacoustic Microscopy for In Vivo 3D Microvasculature Imaging and Segmentation", Advanced Intelligent Systems, 4(9): 202200004, 2022 (SCI,IF=6.214)

[88] [Ningbo Chen, Jia Yu, Liangjian Liu]1, Zhiqiang Xu, Rongkang Gao, Tao Chen, Liang Song, Wei Zheng*, and Chengbo Liu* , "Video-rate high-resolution single-pixel nonscanning photoacoustic microscopy", Biomedical Optics Express,13(7): 3823-3835. 2022. (SCI,IF=3.732)

[87] [Yu Jiang, Xingchen Duan, Liangjian Liu]1, Yang Shi*, Chengbo Liu*, Dan Ding, Yunfeng Deng*, Yang Han, Yanhou Geng*, "NIR-II-absorbing conjugated polymers based on tetra-fused isoindigo ribbons for photothermal conversion and photoacoustic imaging", Cell Reports Physical Science, 3: 100957, 2022. (SCI,IF=6.395)

[86] [Yaguang Ren, Ying Zhang]¹, Honghui He, Liangjian Liu, Xiaojun Wu, Liang Song, Chengbo Liu*, "Optical fiber-based handheld polarized photoacoustic computed tomography for detecting anisotropy of tissues", Quantitative Imaging in Medicine and Surgery ,12(4): 2238-2246 , 2022. (SCI, IF=3.837)

[85] [Zhiqiang Xu, Yinhao Pan]¹, Ningbo Chen, Silue Zeng, Liangjian Liu, Rongkang Gao, Jianhui Zhang, Chihua Fang, Liang Song, Chengbo Liu*, "Visualizing tumor angiogenesis and boundary with polygon-scanning multiscale photoacoustic microscopy", Photoacoustics, 26:100342, 2022. (SCI,IF=8.399)

[84] [Yu Chen, Zhongzheng Yu]¹, Kai Zheng, Yaguang Ren, Meng Wang, Qiang Wu, Feifan Zhou, Chengbo Liu, Liwei Liu, Jun Song* and Junle Qu*,“Degradable mesoporous semimetal antimony nanospheres for near-infrared II multimodal theranostics”, Nature Communications，13: 539 , 2022.  (SCI, IF=14.919)

[83] [Yuejun Lin, Hui-chao Zhou]¹, Ningbo Chen, Yaguang Ren, Rongkang Gao, Qiaojia Li, Yiwen Deng, Xuejiao Han, Xiaoran Zhang, Andy Peng Xiang, Bing Guo*, Chengbo Liu* and Jie Ren*, "Unveiling the improved targeting migration of mesenchymal stem cells with CXC chemokine receptor 3-modifcation using intravital NIR-II photoacoustic imaging", Journal of Nanobiotechnology，20(1): 307, 2022. (SCI，IF=9.913)

[82] [Xuewei Liu; Rongkang Gao; Chiyun Chen]¹; Xiaobo Li; Chen Yu; Yejia Chen; Hongbin Liang; Min Xiao; Lei Dai; Shifeng Qiu; Xiaoyu Xin; Liang Song; Jinbin Liu*; Chengbo Liu*; Jiancheng Xiu*, "Noninvasive photoacoustic computed tomography/ultrasound imaging for the identification of high-risk atherosclerotic plaques", European Journal of Nuclear Medicine and Molecular Imaging, 49(13): 4601-4615, 2022. (SCI, IF=9.236)

[81]Jing Meng, Xueting Zhang, Liangjian Liu, Silue Zeng, Chihua Fang, and Chengbo Liu*, "Depth-extended acoustic-resolution photoacoustic microscopy based on a two-stage deep learning network", Biomedical Optics Express, 13(8): 4386-4397, 2022. (SCI, IF=3.732)

[80]Jianhai Chen, Silue Zeng, Qiang Xue, Yuchuan Hong, Liangjian Liu, Liang Song, Chihua Fang, Hai Zhang, Benguo Wang, Adam C. Sedgwick, Peng Zhang, Jonathan L. Sessler*, Chengbo Liu* and Jingqin Chen*, "Photoacoustic image-guided biomimetic nanoparticles targeting rheumatoid arthritis"，PNAS, 119 (43):  e2213373119, 2022. (SCI，IF=12.779)

[79] [Huangxuan Zhao, Zhenghong Zhou, Feihong Wu, Dongqiao Xiang]1, Hui Zhao, Wei Zhang, Lin Li, Zhong Li, Jia Huang, Hongyao Hu, Chengbo Liu, Tao Wang, Wenyu Liu, Jinqiang Ma*, Fan Yang*, Xinggang Wang*, Chuansheng Zheng*，“Self-supervised learning enables 3D digital subtraction angiography reconstruction from ultra-sparse 2D projection views: A multicenter stud"，Cell report medicine, 3(10): 100775, 2022. (SCI, IF=16.988)

[78]Mingming Yin, Junwei Tong, Fanling Meng, Chenchen Liu, Xiaoming Liu, Fang Fang, Zhenyan He, Xiaojuan Qin, Chengbo Liu, Dong Ni, Yuting Gao,* Huageng Liang,* Xiaoping Zhang,* and Liang Luo*“Near-infrared-II activatable symbiotic 2D carbon−clay nanohybrids for dual imaging-guided combinational cancer therapy”, ACS applied materials & interfaces,14(44): 49471–49482, 2022. (SCI, IF=10.383)

2021

[77] Rongkang Gao, Zhiqiang Xu, Yaguang Ren, Liang Song, Chengbo Liu*, "Nonlinear mechanisms in photoacoustics—Powerful tools in photoacoustic imaging," Photoacoustics, 22: 100243, 2021 (SCI, IF=8.484)

[76]Chen, Yu; Wang, Meng; Zheng, Kai; Ren, Yaguang; Xu, Hao; Yu, Zhongzheng; Zhou, Feifan; Liu, Chengbo; Qu, Junle; Song, Jun*, "Antimony Nanopolyhedrons with Tunable Localized Surface Plasmon Resonances for Highly Effective Photoacoustic-Imaging-Guided Synergistic Photothermal/Immunotherapy", Advanced Materials, 33(18): 2100039, 2021. (SCI, IF=30.849)

[75]Qi, Weizhi; Liang, Xiao; Ji, Yaoyao; Liu, Chengbo; Xi, Lei*, "Optical resolution photoacoustic computed microscopy", Optics Letters, 46(2)：372-375,2021. (SCI, IF=3.776)

[74] [RongkangGao, ZhiqiangXu]¹, LiangSong, Chengbo Liu*, "Breaking Acoustic Limit of Optical Focusing Using Photoacoustic-Guided Wavefront Shaping", Laser & Photonics Reviews, 15(8):2000594, 2021. (SCI, IF=13.138)

[73] [Jingqin Chen, Adam Sedgwick, Sajal Sen]¹, Yaguang Ren, Qinchao Sun, Calvin Chau, Jonathan Arambula, Tridib Sarma*, Liang Song, Jonathan L. Sessler* and Chengbo Liu*, "Expanded porphyrins. Functional photoacoustic imaging agents that operate in the NIR-II region", Chemical Science, 29(12): 9916–9921, 2021. (SCI, IF=9.825)

[72] [Huangxuan Zhao, Ke Li]¹, Fan Yang, Wenhui Zhou, Ningbo Chen, Liang Song, Chuansheng Zheng*, Zhicheng Liu* and Chengbo Liu*, "Customized anterior segment photoacoustic imaging for ophthalmic burn evaluation in vivo", Opto-Electronic Advances, 4(6): 200017, 2021. (SCI, IF=9.636)

[71]Huangxuan Zhao, Ziwen Ke, Fan Yang, Ke Li, Ningbo Chen, Liang Song, Chuansheng Zheng,* Dong Liang,* and Chengbo Liu*，“Deep Learning Enables Superior Photoacoustic Imaging at Ultralow Laser Dosages”，Advanced Science，8(3): 2003097，2021.（SCI，IF=15.840）

[70] [Hui-Chao Zhou, Jie Ren]¹, Yuejun Lin, Duyang Gao, Dehong Hu, Tinghui Yin, Chen Qiu, Xiaoyan Miao, Chengbo Liu, Xin Liu, Hairong Zheng，Rongqin Zheng* and Zonghai Sheng*, "Intravital NIR-II three-dimensional photoacoustic imaging of biomineralized copper sulfide nanoprobes",  Journal of Materials Chemistry B, 9(13): 3005–3014,2021. (SCI, IF=6.331)

[69] Xingang Liu, Yukun Duan, Dehong Hu, Min Wu, Chengjian Chen, Pramila Baban Ghode, Gayathiri Magarajah, Nitish Thakor, Xin Liu, Chengbo Liu, Zonghai Sheng, Hairong Zheng*, and Bin Liu*, "Targeted Photoacoustic Imaging of Brain Tumor Mediated by Neutrophils Engineered with Lipid-Based Molecular Probe",  ACS Materials Letters, 3(9): 1284-1290, 2021. (SCI, IF=8.484)

[68] [Tao Chen, Liangjian Liu, Xiaohui Ma]¹, Ying Zhang, Huadong Liu, Rongqin Zheng, Jie Ren, Huichao Zhou, Yaguang Ren, Rongkang Gao, Ningbo Chen, Hairong Zheng*, Liang Song*, Chengbo Liu*, "Dedicated photoacoustic imaging instrument for human periphery blood vessels: A new paradigm for understanding the vascular health",   IEEE Transactions on Biomedical Engineering , 69(3): 1093-1100, 2021. (SCI, IF=4.538)

[67] [Dongsheng Yua, Yazhou Wanga, Jifeng Chen]¹,  Shuang Liu, Shaohui Deng, Chengbo Liu , Iain McCulloch, Wan Yue*, Du Cheng*, "Co-delivery of NIR-II semiconducting polymer and pH-sensitive doxorubicin-conjugated prodrug for photothermal/chemotherapy", Acta Biomaterialia, https://doi.org/10.1016/j.actbio.2021.10.009,  2021. (SCI, IF=8.947)

[66] Xueting Zhang, Fei Ma, Yuanke Zhang, Jiajun Wang, Chengbo Liu*, Jing Meng*, "Sparse-sampling photoacoustic computed tomography: Deep learning vs. compressed sensing", Biomedical Signal Processing and Control, 71:103233, 2021. (SCI, IF=3.880)

[65] Yinhao Pan, Ningbo Chen, Liangjian Liu, Chengbo Liu, Zhiqiang Xu* and Jianhui Zhang*, "Recovery of photoacoustic images based on accurate ultrasound positioning", Visual Computing for Industry, Biomedicine, and Art ，4(7)：s42492-021-00072-2, 2021. (SCI)

[64] [Jingqin Chen, Adam C. Sedgwick, Sajal Sen] , Yaguang Ren, Qinchao Sun, Calvin Chau,  Jonathan F. Arambula,  Tridib Sarma*, Liang Song, Jonathan L. Sessler * and Chengbo Liu *, "Expanded porphyrins: functional photoacoustic imaging agents that operate in the NIR-II region", Chemical Science, 12(29): 9916–9921,  2021. (SCI, IF=9.969）

2020

[63] Huangxuan Zhao, Ke Li, Ziwen Ke, Ningbo Chen, Songjian Wang, Ke Li, Lidai Wang, Xiaojing Gong, Wei Zheng, Liang Song, Zhicheng Liu*, Dong Liang*, Chengbo Liu*, “A new deep learning method for image deblurring in optical microscopic systems”. Journal of Biophotonics, e201960147, 2020. (SCI，IF=3.914)

[62] [Zhihua Xie, Yanqing Yang, Yaqiong He]¹,  Chengyou Shu, Dong Chen, Jinke Zhang, Jingqin Chen, Chengbo Liu, Zonghai Sheng, Huadong Liu, Jie Liu*, Xiaojing Gong*, Liang Song*, Shaohong Dong*, "In vivo assessment of inflammation in carotid atherosclerosis by noninvasive photoacoustic imaging", Theranostics,10(10): 4694-4704, 2020 (SCI, IF=8.063)

[61] [Chaobang Zhang, Rongkang Gao]¹, Liangliang Zhang, Chengbo Liu*, Zhengmin Yang, and Shulin Zhao*,"Design and synthesis of a ratiometric photoacoustic probe for in situ imaging of zinc Ions in deep tissue in vivo", Analytical Chemistry, 92 (9): 6382-6390, 2020. (SCI, IF=5.15)

[60] [Mingjie Gao, Guangtao Si]¹, Yuanyuan Bai, Lihong V. Wang, Chengbo Liu, and Jing Meng*, "Graphics processing unit accelerating compressed sensing photoacoustic computed tomography with total variation", Applied Optics，59(3): 712-719. 2020. (SCI, IF=2.15)

[59] Yingying Zhou, Siyi Liang, Mingsheng Li,Chengbo Liu, Puxiang Lai*, and Lidai Wang*,"Optical‐resolution photoacoustic microscopy with ultrafast dual‐wavelength excitation", Journal of Biophotonics,13(6): e201960229. 2020. (SCI, IF=3.914)

[58] [Rongkang Gao, Hao Xu, Liangjian Liu]1, Ying Zhang, Ting Yin, Huichao Zhou, Mingjian Sun, Ningbo Chen, Yaguang Ren, Tao Chen, Yinhao Pan, Mingbin Zheng, Tymish Y Ohulchanskyy, Rongqin Zheng, Lintao Cai, Liang Song, Junle Qu*, and Chengbo Liu*, "Photoacoustic visualization of the fluence rate dependence of photodynamic therapy," Biomed Optics Express, 11(8): 4203-4223. 2020. (SCI, IF=3.921)

[57] [Chen Zhang, Huangxuan Zhao, Song Xu]¹, Ningbo Chen, Ke Li, Xinkuan Jiang, Liangjian Liu, Zhicheng Liu, Lidai Wang, Kenneth K. Y. Wong, Jun Zou*, Chengbo Liu*, and Liang Song*, “Multiscale high-speed photoacoustic microscopy based on free-space light transmission and a MEMS scanning mirror”, Optics Letters, 45(16), 2020. (SCI, IF=3.714)

[56] [Bing Cong, Chen Qiu, Yaguang Ren]¹,  Yuanyuan Bai, Muyue Xing, Tinghui Yin, Xiaojing Gong, Liang Song*, Rongqin Zheng*, Chengbo Liu*, "A low cost sensitive transrectal photoacoustic probe with single-fiber bright-field illumination for in vivo canine prostate imaging and real-time biopsy needle guidance" , IEEE Sensors Journal, 20(18): 10974-10980, 2020. (SCI, IF=3.073)

[55] [Jingqin Chen, Ji Qi, Chao Chen]¹, Jianhai Chen, Liangjian Liu, Rongkang Gao, Tiantian Zhang, Liang Song, Dan Ding*, Peng Zhang*, and Chengbo Liu*, "Tocilizumab-conjugated polymer nanoparticles for NIR-II photoacoustic imaging-guided therapy of rheumatoid arthritis", Advanced Materials , 32(37):e2003399. 2020. (SCI, IF=27.398)

[54] Yaxin Hu, Shan Xue, Peizhao Lyu, Xinyu Zhang, Jingqin Chen, Siping Chen, Chengbo Liu*, Xin Chen*, "Opto-acoustic Synergistic Irradiation for Vaporization of Natural Melanin-cored Nanodroplets at Safe Energy Levels and Efficient Sono-chemo-photothermal Cancer Therapy", Theranostics, 10(23): 10448-10465, 2020.(SCI,IF=8.579)

[53]Mingjian Sun, Chao Li, Ningbo Chen, Huangxuan Zhao, Liyong Ma, Chengbo Liu, Yi Shen, Riqiang Lin*, Xiaojing Gong*, "Full three-dimensional segmentation and quantification of tumor vessels for photoacoustic images", Photoacoustics, 20:100212, 2020 (SCI, IF=5.870)

[52] Zhihua Xie, Chengyou Shu, Daya Yang, Hao Chen, Chaobin Chen, Gang Dai, Kwok Ho Lam, Jinke Zhang, Xiatian Wang, Zonghai Sheng, Duyang Gao, Chengbo Liu, Liang Song*, Xiaojing Gong*, “In vivo intravascular photoacoustic imaging at a high speed of 100 frames per second”, Biomedical Optics Express, 11(11): 6721-6731, 2020  (SCI, IF=3.921)

[51] Qiu, Chen; Bai, Yuanyuan; Yin, Tinghui; Miao, Xiaoyan; Gao, Rongkang; Zhou, Huichao; Ren, Jie; Song, Liang; Liu, Chengbo; Zheng, Hairong; Zheng, Rongqin*, “Targeted imaging of orthotopic prostate cancer by using clinical transformable photoacoustic molecular probe”, BMC Cancer, 20(1), 2020(SCI, IF=2.933)

[50] [Yaguang Ren, Adam C. Sedgwick, Jingqin Chen]¹,  Gregory Thiabaud, Calvin V. Chau, Jusung An, Jonathan F. Arambula, Xiao-Peng He, Jong Seung Kim*, Jonathan L. Sessler*, and Chengbo Liu*，“Manganese(II) Texaphyrin: A Paramagnetic Photoacoustic Contrast Agent Activated by Near-IR Light”，Journal of the American Chemical Society，142(38):16156-16160, 2020. (SCI, IF=14.612)

2019

[49] [Chengbo Liu, Jiuling Liao]¹, Longchao Chen, Jianhua Chen, Rubo Ding, Xiaojing Gong, Caimei Cui, Zhiqiang Pang, Wei Zheng*, Liang Song*, "The integrated high-resolution reflection-mode photoacoustic and fluorescence confocal microscopy." Photoacoustics, 14: 12-18, 2019. (SCI, IF=5.250)

[48] [Yanqing Yang, Jingqin Chen]¹,  Yuming Yang, Zhihua Xie, Liang Song, Peng Zhang*, Chengbo Liu*, Jie Liu *, "A 1064 nm excitable semiconducting polymer nanoparticle for photoacoustic imaging of gliomas." Nanoscale ，11: 7754-7760, 2019.（SCI，IF=7.233）

[46] Chengbo Liu, Muyue Xing, Bing Cong, Chen Qiu, Dong He, Congzhi Wang, Yang Xiao, Tinghui Yin, Min Shao, Weibao Qiu, Teng Ma, Xiaojing Gong, Xiong Chen, Hairong Zheng, Rongqin Zheng, Liang Song*, "In vivo transrectal imaging of canine prostate with a sensitive and compact handheld transrectal array photoacoustic probe for early diagnosis of prostate cancer." Biomedical Optics Express， 10(4): 1707-1717, 2019. （SCI，IF=3.482）

[45] [Meng Zhou, Huangxuan Zhao]¹, Haibo Xia, Jiayao Zhang, Zhicheng Liu, Chengbo Liu*, Fei Gao*, "De-noising of photoacoustic sensing and imaging based on combined empirical mode decomposition and independent component analysis." Journal of Biophotonics，12(8), 2019. （SCI，IF=3.768）

[44] [Shan Sun, Jingqin Chen]¹,  Kai Jiang, Zhongdi Tang, Yuhui Wang, Zhougjun Li, Chengbo Liu*, Aiguo Wu*, Hengwei Lin*, "Ce6-Modified Carbon Dots for Multimodal-Imaging-Guided and Single-NIR-Laser-Triggered Photothermal/Photodynamic Synergistic Cancer Therapy by Reduced Irradiation Power." ACS Applied Materials & Interfaces，11(6): 5791-5803, 2019.（SCI，IF=8.097）

[43] [Qian Zhao, Riqiang Lin, Chengbo Liu]1, Jingxiu Zhao, Guangtao Si, Liang Song*, Jing Meng*, "Quantitative analysis on in vivo tumor-microvascular images from optical-resolution photoacoustic microscopy." Journal of Biophotonics, 12(6): e201800421, 2019. (SCI, IF=3.768)

[42] Huangxuan Zhao, Ningbo Chen, Tan Li, Jianhui Zhang, Riqiang Lin, Xiaojing Gong, Liang Song, Kunya Zhang, Zhi Yang, Zhicheng Liu, Chengbo Liu*, "Motion Correction in Optical Resolution Photoacoustic Microscopy." IEEE Transactions on Medical Imaging，38(9): 2139-2150,  2019. (SCI, IF=6.131)

[41][Ning Ding, Xiaoxiao Liu, Ningbo Chen]¹,  Jing Jiang, Huangxuan Zhao, Zhigang Li*, Jianhui Zhang*, Chengbo Liu*, "Lack of association between acupoint sensitization and microcirculatory structural changes in a mouse model of knee osteoarthritis: A pilot study." Journal of Biophotonics, 12(6): e201800458, 2019. (SCI，IF=3.768)

[40] Huixiang Yan, Jingqin Chen, Ying Li, Yuanyuan Bai, Yunzhu Wu, Zonghai Sheng, Liang Song, Chengbo Liu*, Hai Zhang*, "Ultrasmall hybrid protein-copper sulfide nanoparticles for targeted photoacoustic imaging of orthotopic hepatocellular carcinoma with high signal-to-noise ratio." Biomaterials Science, 7(1): 92-103, 2019. (SCI, IF=5.831)

[39] [Bing Guo, Jingqin Chen, Ningbo Chen]¹,  Eshu Middha, Shidang Xu, Yutong Pan, Chengbo Liu*, Bin Liu*, "High-Resolution 3D NIR-II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent." Advanced Materials，31(25), 2019.（SCI，IF= 21.95）

[38] Chen, Qingshan, Chen, Jingqin, He, Mu, Bai, Yuanyuan, Yan, Huixiang, Zeng, Ning, Liu, Fangyan, Wen, Sai, and Song, Liang, Zonghai Sheng,* Chengbo Liu* and Chihua Fang* ,“Novel small molecular dye-loaded lipid nanoparticles with efficient near-infrared-II absorption for photoacoustic imaging and photothermal therapy of hepatocellular carcinoma”, Biomaterials Science, 7(8): 3165-3177, 2019. (SCI, IF= 5.251)

[37] [Hui-Chao Zhou, Ningbo Chen]¹, Huangxuan Zhao, Tinghui Yin, Jianhui Zhang, Wei Zheng, Liang Song, Chengbo Liu*, Rongqin Zheng*, “Optical-resolution photoacoustic microscopy for monitoring vascular normalization during anti-angiogenic therapy ”, Photoacoustics, 15: 100143, 2019. (SCI, IF=5.25 )

[36] Huangxuan Zhao, Ke Li, Ningbo Chen, Kunya Zhang, Lidai Wang, Riqiang Lin, Xiaojing Gong, Liang Song, Zhicheng Liu* and Chengbo Liu*, "Multiscale Vascular Enhancement Filter Applied to In Vivo Morphologic and Functional Photoacoustic", IEEE Photonics Journal, 11(6): 39009112, 2019. (SCI, IF=2.729)

2018

[35] D. Hu, Z.i Sheng*, M. Zhu, X. Wang,  F. Yan, C. Liu, L. Song, M. Qian, X. Liu and H. Zheng*, “Förster Resonance Energy Transfer-Based Dual-Modal Theranostic Nanoprobe for In Situ Visualization of Cancer Photothermal Therapy”, Theranostics, 8(2):410-422, 2018(SCI, IF=8.766).

[34] [M. Li, C. Liu*]¹, X. Gong, R. Zheng, Y. Bai, M. Xing, X. Du, X. Liu, J. Zeng, R. Lin, H. Zhou, S. Wang, G. Lu, W. Zhu, C. Fang, and L. Song*, "Linear array-based real-time photoacoustic imaging system with a compact coaxial excitation handheld probe for noninvasive sentinel lymph node mapping." Biomedical Optics Express, 9(4): 1408-1422, 2018. (SCI, IF=3.337)

[33] J. Chen, X. Li, X. Liu, H. Yan, Z. Xie, Z. Sheng, X. Gong, L. Wang, X. Liu, P. Zhang, H. Zheng, L. Song, and C. Liu*, "Hybrid MoSe2-indocyanine green nanosheets as a high-efficient phototheranostic agent for photoacoustic imaging guided photothermal cancer therapy." Biomaterials Science, 6,1503-1516, 2018. (SCI, IF=4.210)

[32] H. Zhao, G. Wang, R. Lin, X. Gong, L. Song, T. Li, W. Wang, K. Zhang, X. Qian, H. Zhang, L. Li, Z. Liu*, and C. Liu*, "Three Dimensional Hessian matrix based quantitative vascular imaging of rat iris with optical-resolution photoacoustic microscopy." Journal of Biomedical Optics, 23(4)1-11, 2018. (SCI, IF=2.530)

[31] [C. Liu, J. Chen, Y. Zhu]¹, X. Gong, R. Zheng, Ni. Chen, D. Chen, H. Yan, P. Zhang, H. Zheng, Z. Sheng* and Liang Song*, "Highly sensitive MoS2-Indocyanine green hybrid for photoacoustic imaging of orthotopic brain glioma at deep site." Nano-Micro Letters, 10(3), 2018. (SCI, IF=4.849)

[30] [X. Lin, C. Liu, X. Gong, J. Meng]¹, R. Lin, M. Sun*, and L. Song*, "Dual-foci detection in photoacoustic computed tomography with coplanar light illumination and acoustic detection-A phantom study." Journal of Biomedical Optics, 23(5):1-4, 2018. (SCI, IF=2.530)

[29] M. Wu, W. Chen, Y. Chen, H. Zhang, C. Liu, Z. Deng, Z. Sheng, J. Chen, X. Liu, F. Yan* and H. Zheng*, "Focused Ultrasound-Augmented Delivery of Biodegradable Multifunctional Nanoplatforms for Imaging-Guided Brain Tumor Treatment" Advanced Science, 5(4), 1700474, 2018. (SCI, IF=2.530)

[28] Li Y, Lin R, Liu C, Chen J, Liu H, Zheng R, Gong X*, Song L*, "In vivo photoacoustic/ultrasonic dual-modality endoscopy with a miniaturized full field-of-view catheter." Journal of Biophotonics, e201800034, 2018. (SCI, IF=3.914)

[27] [X. Lin, C. Liu]1, Z. Sheng, X. Gong, L. Song, R. Zhang, H. Zheng,* and M. Sun*, “Highly Sensitive Fluorescence and Photoacoustic Detection of Metastatic Breast Cancer in Mice Using Dual-Modal Nanoprobes”, ACS Appl. Mater. Interfaces, 10(31): 26064−26074, 2018. (SCI, IF=8.097)

[26] Yuanyuan Bai, Bing Cong, Xiaojing Gong, Liang Song, Chengbo Liu*, "Compact and low-cost handheld quasibright-field linear-array probe design in photoacoustic computed tomography", Journal of Biomedical Optics, 23(12): 121606, 2018.(SCI, IF=4.486 )

[25] [W. Xu, J. Chen, S. Sun]¹, Z. Tang, K. Jiang, L. Song, Y. Wang,* C. Liu * and H. Lin *, ”Fluorescent and photoacoustic bifunctional probe for the detection of ascorbic acid in biological fluids, living cells and in vivo”, Nanoscale,10(37):17834-17841, 2018. (SCI, IF=7.233)

[24] Zonghai Sheng, Bing Guo, Dehong Hu, Shidang Xu, Wenbo Wu, Weng Heng, Liew  Kui Yao, Jingying Jiang,  Chengbo Liu, Hairong Zheng*, Bin Liu*, "Bright Aggregation‐Induced‐Emission Dots for Targeted Synergetic NIR‐II Fluorescence and NIR‐I Photoacoustic Imaging of Orthotopic Brain Tumors", Advanced Materials, 30(29):1800766, 2018. (SCI, IF=27.398)

[23] Bing Guo, Zonghai Sheng, Dehong Hu, Chengbo Liu, Hairong Zheng,* and Bin Liu*, "Through Scalp and Skull NIR-II Photothermal Therapy of Deep Orthotopic Brain Tumors with Precise Photoacoustic Imaging Guidance", Advanced Materials, 30(35):1802591, 2018.(SCI, IF=27.398)

[22] Jing Meng*, Chengbo Liu, Jeesu Kim, Chulhong Kim, and Liang Song*, "Compressed sensing with a gaussian scale mixture model for limited view photoacoustic computed tomography in vivo", Technology in Cancer Research & Treatment, 17: 1-11, 2018.

[21] Guiying Xu, Xin Bao, Jingqin Chen, Bohan Zhang, Di Li, Ding Zhou, Xiaoyun Wang, Chengbo Liu, Yingli Wang,* and Songnan Qu*, " In Vivo Tumor Photoacoustic Imaging and Photothermal Therapy Based on Supra-(Carbon Nanodots) ", Advanced Healthcare Materials, 8(2):1800995, 2018. (SCI, IF=7.367)

[20] Xin Bao, Ye Yuan, Jingqin Chen, Bohan Zhang, Di Li, Ding Zhou, Pengtao Jing, Guiying Xu, Yingli Wang, Kateřina Holá, Dezhen Shen, Changfeng Wu, Liang Song, Chengbo Liu*, Radek Zbořil* and Songnan Qu*, "In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration", Light-Science & Applications, 7(91) ,2018,(SCI, IF=13.714)

[19] Yi Huang, Xiaoxia Li, Lu Zhang, Xiaoyan Chen, Chengbo Liu, Jingqin Chen, Yong Wang*, and

Xintao Shuai, "Multifunctional Nanoplatform Based on pH-responsive Micelle Coated with Discontinuous Gold Shell for Cancer Photothermo-chemotherapy and Photoacoustic Tomography", Chinese Journal of Polymer Science, 36:1139–1149, 2018.(SCI, IF=3.154)

2017

 [18] Guo, B., Sheng, Z., Kenry, Hu, D., Lin, X., Xu, S., Liu, C., Zheng, H.*, Liu, B.*,  "Biocompatible Conjugated Polymer Nanoparticles for Highly Efficient Photoacoustic Imaging of Orthotopic Brain Tumor in Second Near-Infrared Window", Materials Horizons, 4(6):1151-1156, 2017 (SCI, IF=10.706 ).

[17] Guo B., Sheng Z., Hu D., Li A., Xu S., Manghnani PN., Liu C., Guo L., Zheng H.*, Liu B.* "Molecular Engineering of Conjugated Polymers for Biocompatible Organic Nanoparticles with Highly Efficient Photoacoustic and Photothermal Performance in Cancer Theranostics", Acs Nano., 11(10):10124-10134, 2017 Oct 24. (SCI, IF=13.942).

[16] M. Zhu, Z. Sheng, Y. Jia, D. Hu, X. Liu, X.Xia, C. Liu, P. Wang, X. Wang*, and H. Zheng*, "Indocyanine Green-holo-Transferrin Nanoassemblies for Tumor-Targeted Dual-Modal Imaging and Photothermal Therapy of Glioma", ACS Applied Materials & Interfaces, 9(45):39249-39258, 2017 (SCI, IF=7.502).

2016

[15] [J. Chen, C. Liu]¹, D. Hu, F. Wang, H. Wu, X. Gong, X. Liu, L. Song*, Z. Sheng*, H. Zheng*,  "Single-Layer MoS2 Nanosheets with Amplified Photoacoustic Effect for Highly Sensitive Photoacoustic Imaging of Orthotopic Brain Tumors", Advanced Functional Materials, 26(47): 8715-8725, 2016. (SCI, IF=11.382)

[14] D. Hu, C. Liu, L. Song, H. Cui, G. Gao, P. Liu, Z. Sheng* and L. Cai*, "Indocyanine green–loaded polydopamine–iron ions coordination nanoparticles for photoacoustic/magnetic resonance dual-modal imaging-guided cancer photothermal therapy", Nanoscale, 8(39):11750-11758, 2016. (SCI, IF=7.760)

[13] C. Liu, X. Gong, F. Liu , R. Lin , J. Chen, Z. Wang , L. Song*, J. Chu*, "Advances in imaging techniques and genetically encoded probes for photoacoustic imaging". Theranostics, 6(13): 2414-2430 (2016).（SCI, IF=8.854）

[12] J. Li, H. Xiao, S. J. Yoon, C. Liu, D. Matsuura, W. Tai, L. Song*, M. O’Donnell*, D. Cheng*, X. Gao*. “Functional Photoacoustic Imaging of Gastric Acid Secretion Using pH-Responsive Polyaniline Nanoprobes.” Small, DOI: 10.1002/smll.201601395(2016). (SCI, IF=8.31)

[11] J. Chen, C. Liu, G. Zeng, Y. You, H. Wang, X. Gong, R. Zheng, J. Kim, C. Kim and L. Song*, "Indocyanine Green Loaded Reduced Graphene Oxide for In Vivo Photoacoustic/Fluorescence Dual-Modality Tumor Imaging", Nanoscale Research Letters, 11(1),85-88 (2016).( SCI,  IF: 2.779).

2015

[10] [Y. Li, X. Gong]¹, C. Liu, R. Lin, William Hau, X. Bai, L. Song*, “High-speed intravascular spectroscopic photoacoustic imaging at 1000 A-lines per second with a 0.9 mm diameter catheter,” Journal of Biomedical Optics, 20(6), 065006 (2015).( SCI, IF:2.752).

[9] [J. Mou, C. Liu]¹, P. Li, Y. Chen, H. Xu, C. Wei, L. Song*, J. Shi, H. Chen*, “A Facile Synthesis of Versatile Cu2-xS Nanoprobe for Enhanced MRI and Infrared Thermal/Photoacoustic Multimodal Imaging,” Biomaterials, 57, 12-21(2015) (SCI, IF: 8.312).

[8] J. Mou, P. Liu, C. Liu, H. Xu, L. Song, J. Wang, K. Zhang, Y. Chen, J. Shi, and H. Chen, “Ultrasmall Cu2-xS Nanodots for Highly Efficient Photoacoustic Imaging-Guided Photothermal Therapy,” Small, 11(19), 2275-2283(2015) (SCI, IF: 7.514).

[7] D. Gao, P. Zhang, C. Liu, C. Chen, G. Gao, Y. Wu, Z. Sheng, L. Song, L. Cai, “Compact chelator-free Ni-integrated CuSnanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging,” Nanoscale, 7, 17631-17636(2015) (SCI, IF: 7.760).

[6] C. Lee, J. Kim, Y. Zhang, M. Jeon, C. Liu, L. Song, J. Lovell, C. Kim, “Dual-color photoacoustic lymph node imaging using nanoformulatednaphthalocyanines,” Biomaterials, 73, 142-148(2015) (SCI, IF: 8.312).

2014

[5] [H. Wang, C. Liu]¹, X. Gong, D. Hu, R. Lin, Z. Sheng, C. Zheng, M. Yan, J. Chen, L. Cai and L. Song*, "In vivo photoacoustic molecular imaging of breast carcinoma with folate receptor-targeted indocyanine green nanoprobes," Nanoscale, 6, 14270-14279 (2014) (SCI, IF: 6.739).
[4] J. Jian, C. Liu, Y. Gong, L. Su, B. Zhang, Z. Wang, D. Wang, Y. Zhou, F. Xu, P. Li, Y. Zheng, L. Song*, and X. Zhou*, "India ink incorporated multifunctional phase-transition nanaodroplets for photoacoustic/ultrasound dual-modality imaging and photoacoustic effect based tumor therapy," Theranostics, 4, 1026-1038 (2014) (SCI, IF: 7.827).
[3] X. Bai, X. Gong, W. Hau, J. Zheng, C. Liu, R. Lin, X. Zou, C. Zeng, H. Zheng, and L. Song*, “Intravascular optical-resolution photoacoustic tomography with a 1.1 mm diameter catheter,” PLOS One,9, e92463-e92463 (2014) (SCI, IF: 4.24).
[2] J. Meng, C. Liu, J. Zheng, R. Lin, and L. Song*, “Compressed sensing based virtual-detector photoacoustic microscopy in vivo,” Journal of Biomedical Optics,19, 036003 (2014) (SCI, IF: 3.16).
[1] [Z. Yang, J. Chen], J. Yao, R. Lin, J. Meng, C. Liu, J. Yang, X. Li, L. Wang, and L. Song*, “Multi-parametric quantitative microvascular imaging with optical-resolution photoacoustic microscopy in vivo,” Optics Express,22,1500-1511 (2014) (SCI, IF: 3.59).