Research Center for Biomedical Optics and Molecular Imaging

    Researcher Liu Chengbo's Team Homepage

Team Members

Dr. Liu Chengbo, Researcher and Ph.D. Supervisor

Dr. Liu Chengbo is a Professor, Ph.D. supervisor, and recipient of the National Excellent Young Scientist Award. He

 serves as an editorial board member for the JCR Q1 journal "Photoacoustics," and is the Associate Editor of the 

journal "Biophotonics Discovery." He also holds the position of Deputy Secretary-General of the Biomedical 

Photonics Branch of the Chinese Optical Society and has been recognized as a Senior Member by SPIE/OSA/IEEE. 

Dr. Liu received his Bachelor's degree in Biomedical Engineering from Xi'an Jiaotong University in 2007, and 

completed his Ph.D. in Biophysics from the same university in 2012. He conducted joint training at ** Duke 

University from 2009 to 2011. His primary research focuses on photoacoustic imaging technology and

 instruments, as well as translational research. He proposed a theoretical method for zero-background targeted 

photoacoustic imaging and developed micro/meso/macro-scale photoacoustic imaging instruments, achieving

 imaging of peripheral blood vessels in humans.Dr. Liu has led several research projects, including those funded

 by the Ministry of Science and Technology, the National Natural Science Foundation of China, and the Chinese

 Academy of Sciences. He has also served as the responsible collaborator for projects funded by the National 

Natural Science Foundation and major instrument development programs. He has published over 100 SCI papers, 

with more than 60 as first/corresponding author in journals such as PNAS. His work has been cited over 4000

 times in Web of Science, with an H-index of 40. He has also been involved in peer review for journals such as 

Nature BME and Nature Communications.



  • Email:cb.liu@siat.ac.cn
  • Dr. Chen Jingqin, Associate Researcher and Master's Supervisor

    Jingqin Chen , Ph.D., Associate Researcher, Master's Supervisor, Shenzhen Overseas High-level Talent, Member of the CAS Youth Promotion Association. Dr. Chen joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences in July 2014. He obtained his Ph.D. in Biochemistry and Molecular Biology from the University of Chinese Academy of Sciences. From 2019 to 2020, he worked on molecular probe synthesis in the research group of Academician Sessler at the University of Texas at Austin. His main research interests include targeted regulation of the inflammatory microenvironment and molecular diagnosis and therapy. In recent years, he has been the principal investigator of several projects funded by the National Natural Science Foundation of China, including the Youth and General Programs, as well as the CAS Youth Promotion Association Talent Program. He has also participated in multiple research projects, including the National Key R&D Program and provincial and municipal natural science funds. He has published over 40 high-level SCI papers, with 18 of them as the first/corresponding author in journals such as PNAS, JACS, and AM. His publications have been cited over 1600 times according to Google Scholar, with an H-index of 21. He has also been granted 5 invention patents.




  • Email:jq.chen@siat.ac.cn
  • Dr. Gaorong Kang, Associate Researcher and Master's Supervisor.

    Rongkang Gao , Ph.D., Associate Researcher, Master's Supervisor, Shenzhen Overseas High-level Talent, graduated from the University of New South Wales, Australia, in 2018 with a Ph.D. degree in Mechanical Engineering. In November 2018, she joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, focusing on research areas such as the theoretical mechanisms of photoacoustics, development and application of high-resolution and high-sensitivity photoacoustic technology, and research on photoacoustic imaging algorithms. She has published more than 20 high-level SCI journal papers in internationally renowned academic journals, including 13 as the first author, in journals such as Laser & Photonics Reviews, Photoacoustics, Analytical Chemistry, and Physics of Fluids. She has filed 13 invention patents. In recent years, she has been the principal investigator of one National Natural Science Foundation project, two Shenzhen Basic Research Grants, and one China Postdoctoral Science Foundation project. She has also participated as a core member in multiple research projects, including the National Key R&D Program and major research programs funded by the National Natural Science Foundation. She serves as a reviewer for journals such as Photoacoustics.




  • Email:rk.gao@siat.ac.cn
  • Dr. Ren Yaguang, Assistant Researcher.

    Yaguang  Ren , PhD, Assistant Researcher. She obtained her Master's degree in Optical Engineering from Tianjin University in 2013, where she mainly focused on research in high-precision optical detection and fiber sensing based on white-light interference. In 2014, she entered the Department of Biomedical Engineering at ** University for her doctoral studies, specializing in the field of magnetic resonance imaging reconstruction. She received her PhD in Bioengineering in 2018 and subsequently worked as a short-term visiting scholar in the Department of Life Sciences, where she primarily conducted research on single-molecule detection based on total internal reflection-fluorescence resonance energy transfer. In January 2019, she joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, where her main research interests lie in the theoretical and methodological development of multi-scale low-rank and sparse cardiac photoacoustic image reconstruction.



  • Email:yg.ren@siat.ac.cn
  • Dr. Xu Zhiqiang , Assistant Researche

    Zhiqiang  Xu  , Ph.D., is an Assistant Researcher. He obtained his Ph.D. degree in Information and Communication Engineering from Wuhan University of Technology in 2020. During his doctoral studies, he conducted joint training at the University of Virginia. He has published 4 SCI papers as first author or corresponding author, as well as 3 conference papers. In July 2020, he joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, where his main research focus is on the development and application of cross-scale, high-speed photoacoustic microscopy imaging technology.


  • Email:zq.xu@siat.ac.cn
  • Dr. Song Zheng, Ph.D., Postdoctoral researcher.

    Dr. Zheng Song, a postdoctoral researcher, graduated from Shanxi University in 2023 with a Ph.D. degree in Optics. During his doctoral studies, he focused on the research of all-optical photoacoustic imaging and published one SCI paper as the first author. He also obtained one patent in China. In September 2023, Dr. Song joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, as a postdoctoral researcher. His current research mainly involves single-pixel photoacoustic imaging.


  • Email:z.song@siat.ac.cn
  • Chen Ningbo, Ph.D. candidate and Assistant Researcher in service

    Ningbo Chen ,a Master's degree holder and an Assistant Researcher. He graduated from Guangzhou University in 2019 with a major in Mechanical Engineering, obtaining a Master's degree. Currently, he is primarily engaged in the design of photoacoustic microscopy systems and their biomedical applications. Chen has published or collaborated on six journal papers, including Advanced Materials, Journal of Biophotonics, and Photoacoustics. Additionally, he has applied for two Chinese invention patents.



  • Email:nb.chen@siat.ac.cn
  • Liu Liangjian, PhD candidate.

    Liu Liangjian, male, currently pursuing a Ph.D. degree. He obtained his Bachelor's degree in Mechanical Design, Manufacturing, and Automation from Harbin Institute of Technology, School of Mechatronics Engineering in 2013, and his Master's degree in Mechanical Engineering in 2015. In September 2018, he joined the Institute of Biomedical and Health Engineering at the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, where he focuses on the development of photoacoustic devices. He has published more than ten SCI papers and has filed over ten invention patents.

  • Email:lj.liu@siat.ac.cn
  • Zeng Siliue, Visiting Ph.D. Student at Southern Medical University

    Zeng Silyue is a visiting doctoral student at Southern Medical University, specializing in the field of surgery. He obtained his master's degree in surgery from Southern Medical University in July 2020. His current research focuses on the application of photoacoustic molecular imaging technology in liver, gallbladder, and pancreatic diseases. He has published multiple SCI and core papers, and has participated in drafting two expert consensus on digital intelligent diagnosis and treatment technology. He has also contributed to the compilation of the books "Digital Biliary Surgery" and "Biliary Tract Surgery: Application of Digital Technology".



  • Email:sl.zeng@siat.ac.cn
  • Dong Shirui, a PhD candidate.

    Dong Shirui, male, currently a Ph.D. candidate. He graduated with a Bachelor's degree in Measuring and Control Technology and Instruments from the School of Mechanical Engineering at Xi'an Jiaotong University in 2020. In 2023, he obtained a Master's degree in Energy and Power Engineering from the School of Energy and Power Engineering at Xi'an Jiaotong University. In September 2023, he joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences. His current research focus is on novel photoacoustic systems.




  • Email:sr.dong@siat.ac.cn
  • News Updates

    Research Directions

    Paper Achievements

    Representative Projects

    project nameProject categoryFunding agencyproject numberProject timeproject leader
    Development of high spatial otemporal resolution acoustic BOLD brain imaging instrumentNational major scientific research instrument research and development projectNational nature
    Science Foundation Committee
    823278052024.01-2028.12Person in charge of the partner
    Photoacoustic molecular imagingExcellent Youth FundNational nature
    Science Foundation Committee
    821220342022.01-2024.12Chengbo liu
    Multiscale, multi-parametric photoacoustic function and molecular imaging of tumor vesselsMajor research plan
    Cultivation project
    National nature
    Science Foundation Committee
    920591082021.01-2023.12Chengbo liu
    Photoacoustic magnetic multimodal imaging system for studies of tissue morphology and function in early prostate cancerMajor instrument developmentNational nature
    Science Foundation Committee
    819278072020.01-2024.12partner
    leading official
    Continuous non-invasive peripheral vascular photoacoustic imaging is used to study the mechanism of vascular injury repairMajor research plan
    Cultivation project
    National nature
    Science Foundation Committee
    917391172018.01-2020.12Chengbo liu
    Research on photoacoustic ultrasonic dual-mode imaging and photoacoustic therapy based on new liquid fluorocarbon nanoparticlesYouth fundNational nature
    Science Foundation Committee
    614052342015.01-2017.12Chengbo liu
    Basic research of ultrasound / photoacoustic molecular imaging fusion guiding the early and precise interventional diagnosis and treatment of prostate cancerKey fundsNational nature
    Science Foundation Committee
    814300382015.01-2019.12partner
    leading official
    Super-resolution photoacoustic imaging analyzerBasic scientific research conditions of the national key research and development program and the research and development of major scientific instruments and equipmentMinistry of Science and Technology2023YFF07153002023.12-2026.11Co-project leader
    Photoacoustic / ultrasound dual-mode multispectral functional imaging system development
    National key research and development plan for diagnosis and treatment equipment and biomedical materialsMinistry of Science and Technology2023YFC24117002023.11-2027.10Person in charge of the partner
    Photoacoustic imaging monitoring of tumor oxygen metabolism with key molecular markersThe Ministry of Science and Technology focuses on research and development
    international co-operation
    Ministry of Science and Technology2022YFE01323002023.01-2024.12Chengbo liu
    Cross-scale multi-parametric photoacoustic fast imaging accurately identifies tumor boundariesThe Ministry of Science and Technology focuses on research and development
    strategic cooperation
    Ministry of Science and Technology2021YFE02022002021.08-2023.07Chengbo liu
    Research on the key scientific issues of accurate diagnosis and treatment technology of brain glioma973 ProjectMinistry of Science and Technology2015CB7555002015.01-2019.08Photoacoustic imaging
    leading official
    Photoacoustic ultrasound bimodal imaging instrument for marmoset brain science researchScientific research instruments and equipment
    Development project
    Academia SinicaYJKYYQ201900782020.01-2021.12Chengbo liu
    Outstanding member of the Youth Innovation Promotion Association, Chinese Academy of SciencesTalent-Youth promotion meetingAcademia Sinica20193522024.01-2027.12Chengbo liu
    Member of the Youth Innovation Promotion Association, Chinese Academy of SciencesTalent-Youth promotion meetingAcademia Sinica20193522019.01-2022.12Chengbo liu
    Key technology innovation team for cross-scale multimodal brain imagingkey technologyAcademia SinicaGJJSTD202100032018.05-2021.01
    -2023.12
    Photoacoustic imaging
    leading official
    Mechanism of 3 D dynamic photoacoustic imaging of biological tissuesfundamental research
    accented term
    Shenzhen
    Kechuang committee
    JCYJ202208181014030082023.01-2025.12Chengbo liu
    Basic research on functional imaging of photoacoustic brainfundamental research
    accented term
    Shenzhen
    Kechuang committee
    JCYJ202001091412228922020.11-2023.11partner
    leading official
    Research on the parallel acquisition of high-speed photoacoustic human peripheral vascular imaging technologyfundamental research
    accented term
    Shenzhen
    Kechuang committee
    JCYJ201704131531295702017.07-2020.07Chengbo liu
    Novel highly sensitive photoacoustic imaging probe and system suitable for clinical tumor imagingfundamental research
    accented term
    Shenzhen
    Kechuang committee
    JCYJ201605311750409762017.01-2018.12Chengbo liu
    Research on accurate surgical navigation instruments for tumor light / sound multimodal molecular imagingIndustry-university-research collaboration
    Major projects will be innovated
    Guangzhou City
    Kechuang committee
    E2016040201442016.04-2019.03partner
    leading official






    Granted patent

    title of inventioninventorclassifyApply for the countrypatent number
    Photoacoustic imaging methods, computer equipment, systems, and storage mediaChengbo Liu; Yinhao Pan; Ningbo Chen; Zhiqiang Xu; Liangjian Liu; Rongkang Gao; Ying Zhang inventChinaZL 2020 1 1072769.6
    Polarized photoacoustic imaging probe and photoacoustic imaging deviceChengbo Liu; Yaguang Ren; Ying Zhang; Rongkang Gao; Yinhao Pan inventChinaZL 2020 1 0790562.6
    A panoramic optical follower device and its photoacoustic imaging systemChengbo Liu; Ying Zhang; Tao Chen; Liangjian Liu; Yin Pan; Hao; Ningbo Chen; Rongkang Gao; Yaguang Ren inventChinaZL 2020 1 0451546.4
    Type of photoacoustic signal processing device and processing methodZhiqiang Xu; Chengbo Liu; Yinhao Pan inventChinaZL 2020 1 1072782.1
    Optical imaging methods, related devices, and systemsChengbo Liu; Ke Li; Songjian Wang; Huangxuan Zhao; Liangjian Liu; Ningbo Chen; Liang Song; Zhicheng Liu inventChinaZL 2019 1 0844194.6
    Method and device for monitoring the temperature distribution of the ablation thermal fieldChengbo Liu; Yuan Yuan Bai; Liang Song; Rongqin Zheng; Bing Cong; Kai Li; Xiaojing Gong inventChinaZL 2018 1 0836284.6
    Photoacoustic probe and photoacoustic imaging systemChengbo Liu; Liang Song; Muyue Xing; Jingqin Chen inventChinaZL 2017 1 0046338.4
    A method for preparing a molecular probe for photoacoustic imaging and photothermal therapyJingqin Chen; Chengbo Liu; Liang Song; Xueshen Li; Chihua Fang inventChinaZL 2017 1 1219081.4
    Photoacoustic imaging fixture and the photoacoustic imaging device for its applicationLiang Song; Mucong Li; Chengbo Liu; Muyue Xing inventChinaZL 2017 1 0116558.X
    Molybdenum disulfide-diao green nanocomposite particles and their preparation methods and applicationsYing Zhu; Liang Song; Zonghai Sheng; Chengbo Liu; Jingqin Chen inventChinaZL 2017 1 0373187.3
    Multimodal imaging system and its imaging methodsLiang Song; Kang Yan; Xiaojing Gong;Riqiang Lin; Chengbo Liu; Xiaoyang Liu inventChinaZL 2017 1 0273436.1
    A dark-field illumination acoustic resolution photoacoustic microscopeLiang Song; Wei Song; Chengbo Liu; Jingqin Chen; Guang Zeng inventChinaZL 2015 1 0979703.8
    Hand photoacoustic imaging probeLiang Song; Mucong Li; Chengbo Liu;Riqiang LininventChinaZL 2015 1 0490944.6
    Type of nanodrug complexes loaded with paclitaxel and their preparation methodsJingqin Chen; Liang Song; Chengbo Liu;Riqiang LininventChinaZL 2014 1 0802539.9
    Hand photoacoustic imaging probeLiang Song; Chengbo Liu; XiaoSong Bai;Riqiang LininventChinaZL 2013 1 0323898.1
    Simple handheld photoacoustic imaging probeLiang Song; Chengbo Liu; XiaoSong Bai;Riqiang LininventChinaZL 2013 1 0323890.5
    Photoacoustic imaging scanning deviceChengbo Liu; Liangjian Liu; Zhenjie Lai; Bin Xu; Zhiqiang XupracticalChinaZL 2023 2 0409079.8
    Photoacoustic signal acquisition device and photoacoustic imaging systemChengbo Liu; Tao Chen; Liang Song; Ying Zhang; Liangjian Liu; Rongkang Gao; Yaguang Ren; Yanhao Pan practicalChinaZL 2020 2 2902035.8
    A photoacoustic microscopy imaging deviceChengbo Liu; Ningbo Chen; Jianhui Zhang; Baiquan Wang; Liangjian Liu practicalChinaZL 2018 2 2255972.1
    Photoacoustic imaging probe and photoacoustic imaging systemChengbo Liu; Yuan Yuan Bai; Liang Song; Xuemin Du practicalChinaZL 2018 2 1643435.8
    Type of probe and probe positioning systemChengbo Liu; Yuan Yuan Bai; Liang Song; Rongqin Zheng; Yan early spring; Kai Li; Bing Cong; Xiaojing Gong practicalChinaZL 2018 2 1320908.0
    Photoacoustic imaging systemChengbo Liu; Liang Song; Yuan Yuan Bai; Rongqin Zheng; Chen Qiu practicalChinaZL 2018 2 1252102.2
    An animal eye fixation device for the photoacoustic imaging systemGuangsong Wang; Chengbo Liu; Liang Song; Huangxuan Zhao; Bing Cong practicalChinaZL 2017 2 1356568.2
    A photoacoustic microimaging systemLiang Song; Chengbo Liu; Guangsong Wang practicalChinaZL 2017 2 0131354.9
    Multimode imaging systemDong Liang; Xuda Hong; Wei Shi; Xiaojing Gong; Chengbo Liu; Zhanli Hu;Riqiang LinpracticalChinaZL 2017 2 1812517.6
    Hand photoacoustic imaging probeLiang Song; Mucong Li; Chengbo Liu;Riqiang LinpracticalChinaZL 2015 2 0605201.4








    Former Team Members

    Postdoctoral / Research Associate / Research Associate / Visiting Scholar
    order numbersurname and personal namegraduate institutionsIn hospital timeIn the school positionThe current unitThe current position
    1 Tao ChenThe University of the Chinese Academy of Sciences2019.07-2023.08Postdoctoral / AssociateBeijing Institute of TechnologyFull-time teacher
    2 Dong HeXi'an Jiao Tong University2018.07-2019.07Research assistantThe Hong Kong University of Science and Technologypost-doctoral
    3 Chen ZhangSCU2018.07-2021.10Postdoctoral / AssociateInformation occupation in ShenzhenFull-time teacher
    4 Xinkuan JiangUniversity On The Mountain Of Swallows2017.09-2018.05Research assistantTsinghua Universitymechanical engineer

    5 Bing CongKyoto University2017.06-2019.09post-doctoralInnocent lasermedical image
    6 Huichao ZhouZhongshan University2017.04-2022.01visiting scholarUniversity of Louvainpost-doctoral
    7Yuanyuan BaiZhejiang University2016.11-2020.01Research assistantZhongke fly testOptical engineer
    8 Guangsong WangCentral South University2016.08-2017.09Research assistantLuohu District construction supervision and housing security centerLevel 8 management post staff
    9Muyue XingNankai University2016.07-2017.11Research assistantShenzhen Universityexperimentalist
    10 Mucong LiHarbin Institute of Technology2014.07-2016.11Research assistantDeepsight Technology IncUltrasound engineer