Research Center for Biomedical Optics and Molecular Imaging
Dr. Liu Chengbo is a Professor, Ph.D. supervisor, and recipient of the National Excellent Young Scientist Award. He
serves as an editorial board member for the JCR Q1 journal "Photoacoustics," and is the Associate Editor of the
journal "Biophotonics Discovery." He also holds the position of Deputy Secretary-General of the Biomedical
Photonics Branch of the Chinese Optical Society and has been recognized as a Senior Member by SPIE/OSA/IEEE.
Dr. Liu received his Bachelor's degree in Biomedical Engineering from Xi'an Jiaotong University in 2007, and
completed his Ph.D. in Biophysics from the same university in 2012. He conducted joint training at ** Duke
University from 2009 to 2011. His primary research focuses on photoacoustic imaging technology and
instruments, as well as translational research. He proposed a theoretical method for zero-background targeted
photoacoustic imaging and developed micro/meso/macro-scale photoacoustic imaging instruments, achieving
imaging of peripheral blood vessels in humans.Dr. Liu has led several research projects, including those funded
by the Ministry of Science and Technology, the National Natural Science Foundation of China, and the Chinese
Academy of Sciences. He has also served as the responsible collaborator for projects funded by the National
Natural Science Foundation and major instrument development programs. He has published over 100 SCI papers,
with more than 60 as first/corresponding author in journals such as PNAS. His work has been cited over 4000
times in Web of Science, with an H-index of 40. He has also been involved in peer review for journals such as
Nature BME and Nature Communications.
Jingqin Chen , Ph.D., Associate Researcher, Master's Supervisor, Shenzhen Overseas High-level Talent, Member of the CAS Youth Promotion Association. Dr. Chen joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences in July 2014. He obtained his Ph.D. in Biochemistry and Molecular Biology from the University of Chinese Academy of Sciences. From 2019 to 2020, he worked on molecular probe synthesis in the research group of Academician Sessler at the University of Texas at Austin. His main research interests include targeted regulation of the inflammatory microenvironment and molecular diagnosis and therapy. In recent years, he has been the principal investigator of several projects funded by the National Natural Science Foundation of China, including the Youth and General Programs, as well as the CAS Youth Promotion Association Talent Program. He has also participated in multiple research projects, including the National Key R&D Program and provincial and municipal natural science funds. He has published over 40 high-level SCI papers, with 18 of them as the first/corresponding author in journals such as PNAS, JACS, and AM. His publications have been cited over 1600 times according to Google Scholar, with an H-index of 21. He has also been granted 5 invention patents.
Rongkang Gao , Ph.D., Associate Researcher, Master's Supervisor, Shenzhen Overseas High-level Talent, graduated from the University of New South Wales, Australia, in 2018 with a Ph.D. degree in Mechanical Engineering. In November 2018, she joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, focusing on research areas such as the theoretical mechanisms of photoacoustics, development and application of high-resolution and high-sensitivity photoacoustic technology, and research on photoacoustic imaging algorithms. She has published more than 20 high-level SCI journal papers in internationally renowned academic journals, including 13 as the first author, in journals such as Laser & Photonics Reviews, Photoacoustics, Analytical Chemistry, and Physics of Fluids. She has filed 13 invention patents. In recent years, she has been the principal investigator of one National Natural Science Foundation project, two Shenzhen Basic Research Grants, and one China Postdoctoral Science Foundation project. She has also participated as a core member in multiple research projects, including the National Key R&D Program and major research programs funded by the National Natural Science Foundation. She serves as a reviewer for journals such as Photoacoustics.
Yaguang Ren , PhD, Assistant Researcher. She obtained her Master's degree in Optical Engineering from Tianjin University in 2013, where she mainly focused on research in high-precision optical detection and fiber sensing based on white-light interference. In 2014, she entered the Department of Biomedical Engineering at ** University for her doctoral studies, specializing in the field of magnetic resonance imaging reconstruction. She received her PhD in Bioengineering in 2018 and subsequently worked as a short-term visiting scholar in the Department of Life Sciences, where she primarily conducted research on single-molecule detection based on total internal reflection-fluorescence resonance energy transfer. In January 2019, she joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, where her main research interests lie in the theoretical and methodological development of multi-scale low-rank and sparse cardiac photoacoustic image reconstruction.
Zhiqiang Xu , Ph.D., is an Assistant Researcher. He obtained his Ph.D. degree in Information and Communication Engineering from Wuhan University of Technology in 2020. During his doctoral studies, he conducted joint training at the University of Virginia. He has published 4 SCI papers as first author or corresponding author, as well as 3 conference papers. In July 2020, he joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, where his main research focus is on the development and application of cross-scale, high-speed photoacoustic microscopy imaging technology.
Dr. Zheng Song, a postdoctoral researcher, graduated from Shanxi University in 2023 with a Ph.D. degree in Optics. During his doctoral studies, he focused on the research of all-optical photoacoustic imaging and published one SCI paper as the first author. He also obtained one patent in China. In September 2023, Dr. Song joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, as a postdoctoral researcher. His current research mainly involves single-pixel photoacoustic imaging.
Ningbo Chen ,a Master's degree holder and an Assistant Researcher. He graduated from Guangzhou University in 2019 with a major in Mechanical Engineering, obtaining a Master's degree. Currently, he is primarily engaged in the design of photoacoustic microscopy systems and their biomedical applications. Chen has published or collaborated on six journal papers, including Advanced Materials, Journal of Biophotonics, and Photoacoustics. Additionally, he has applied for two Chinese invention patents.
Liu Liangjian, male, currently pursuing a Ph.D. degree. He obtained his Bachelor's degree in Mechanical Design, Manufacturing, and Automation from Harbin Institute of Technology, School of Mechatronics Engineering in 2013, and his Master's degree in Mechanical Engineering in 2015. In September 2018, he joined the Institute of Biomedical and Health Engineering at the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, where he focuses on the development of photoacoustic devices. He has published more than ten SCI papers and has filed over ten invention patents.
Zeng Silyue is a visiting doctoral student at Southern Medical University, specializing in the field of surgery. He obtained his master's degree in surgery from Southern Medical University in July 2020. His current research focuses on the application of photoacoustic molecular imaging technology in liver, gallbladder, and pancreatic diseases. He has published multiple SCI and core papers, and has participated in drafting two expert consensus on digital intelligent diagnosis and treatment technology. He has also contributed to the compilation of the books "Digital Biliary Surgery" and "Biliary Tract Surgery: Application of Digital Technology".
Dong Shirui, male, currently a Ph.D. candidate. He graduated with a Bachelor's degree in Measuring and Control Technology and Instruments from the School of Mechanical Engineering at Xi'an Jiaotong University in 2020. In 2023, he obtained a Master's degree in Energy and Power Engineering from the School of Energy and Power Engineering at Xi'an Jiaotong University. In September 2023, he joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences. His current research focus is on novel photoacoustic systems.
project name | Project category | Funding agency | project number | Project time | project leader |
Development of high spatial otemporal resolution acoustic BOLD brain imaging instrument | National major scientific research instrument research and development project | National nature Science Foundation Committee | 82327805 | 2024.01-2028.12 | Person in charge of the partner |
Photoacoustic molecular imaging | Excellent Youth Fund | National nature Science Foundation Committee | 82122034 | 2022.01-2024.12 | Chengbo liu |
Multiscale, multi-parametric photoacoustic function and molecular imaging of tumor vessels | Major research plan Cultivation project | National nature Science Foundation Committee | 92059108 | 2021.01-2023.12 | Chengbo liu |
Photoacoustic magnetic multimodal imaging system for studies of tissue morphology and function in early prostate cancer | Major instrument development | National nature Science Foundation Committee | 81927807 | 2020.01-2024.12 | partner leading official |
Continuous non-invasive peripheral vascular photoacoustic imaging is used to study the mechanism of vascular injury repair | Major research plan Cultivation project | National nature Science Foundation Committee | 91739117 | 2018.01-2020.12 | Chengbo liu |
Research on photoacoustic ultrasonic dual-mode imaging and photoacoustic therapy based on new liquid fluorocarbon nanoparticles | Youth fund | National nature Science Foundation Committee | 61405234 | 2015.01-2017.12 | Chengbo liu |
Basic research of ultrasound / photoacoustic molecular imaging fusion guiding the early and precise interventional diagnosis and treatment of prostate cancer | Key funds | National nature Science Foundation Committee | 81430038 | 2015.01-2019.12 | partner leading official |
Super-resolution photoacoustic imaging analyzer | Basic scientific research conditions of the national key research and development program and the research and development of major scientific instruments and equipment | Ministry of Science and Technology | 2023YFF0715300 | 2023.12-2026.11 | Co-project leader |
Photoacoustic / ultrasound dual-mode multispectral functional imaging system development | National key research and development plan for diagnosis and treatment equipment and biomedical materials | Ministry of Science and Technology | 2023YFC2411700 | 2023.11-2027.10 | Person in charge of the partner |
Photoacoustic imaging monitoring of tumor oxygen metabolism with key molecular markers | The Ministry of Science and Technology focuses on research and development international co-operation | Ministry of Science and Technology | 2022YFE0132300 | 2023.01-2024.12 | Chengbo liu |
Cross-scale multi-parametric photoacoustic fast imaging accurately identifies tumor boundaries | The Ministry of Science and Technology focuses on research and development strategic cooperation | Ministry of Science and Technology | 2021YFE0202200 | 2021.08-2023.07 | Chengbo liu |
Research on the key scientific issues of accurate diagnosis and treatment technology of brain glioma | 973 Project | Ministry of Science and Technology | 2015CB755500 | 2015.01-2019.08 | Photoacoustic imaging leading official |
Photoacoustic ultrasound bimodal imaging instrument for marmoset brain science research | Scientific research instruments and equipment Development project | Academia Sinica | YJKYYQ20190078 | 2020.01-2021.12 | Chengbo liu |
Outstanding member of the Youth Innovation Promotion Association, Chinese Academy of Sciences | Talent-Youth promotion meeting | Academia Sinica | 2019352 | 2024.01-2027.12 | Chengbo liu |
Member of the Youth Innovation Promotion Association, Chinese Academy of Sciences | Talent-Youth promotion meeting | Academia Sinica | 2019352 | 2019.01-2022.12 | Chengbo liu |
Key technology innovation team for cross-scale multimodal brain imaging | key technology | Academia Sinica | GJJSTD20210003 | 2018.05-2021.01 -2023.12 | Photoacoustic imaging leading official |
Mechanism of 3 D dynamic photoacoustic imaging of biological tissues | fundamental research accented term | Shenzhen Kechuang committee | JCYJ20220818101403008 | 2023.01-2025.12 | Chengbo liu |
Basic research on functional imaging of photoacoustic brain | fundamental research accented term | Shenzhen Kechuang committee | JCYJ20200109141222892 | 2020.11-2023.11 | partner leading official |
Research on the parallel acquisition of high-speed photoacoustic human peripheral vascular imaging technology | fundamental research accented term | Shenzhen Kechuang committee | JCYJ20170413153129570 | 2017.07-2020.07 | Chengbo liu |
Novel highly sensitive photoacoustic imaging probe and system suitable for clinical tumor imaging | fundamental research accented term | Shenzhen Kechuang committee | JCYJ20160531175040976 | 2017.01-2018.12 | Chengbo liu |
Research on accurate surgical navigation instruments for tumor light / sound multimodal molecular imaging | Industry-university-research collaboration Major projects will be innovated | Guangzhou City Kechuang committee | E201604020144 | 2016.04-2019.03 | partner leading official |
title of invention | inventor | classify | Apply for the country | patent number |
Photoacoustic imaging methods, computer equipment, systems, and storage media | Chengbo Liu; Yinhao Pan; Ningbo Chen; Zhiqiang Xu; Liangjian Liu; Rongkang Gao; Ying Zhang | invent | China | ZL 2020 1 1072769.6 |
Polarized photoacoustic imaging probe and photoacoustic imaging device | Chengbo Liu; Yaguang Ren; Ying Zhang; Rongkang Gao; Yinhao Pan | invent | China | ZL 2020 1 0790562.6 |
A panoramic optical follower device and its photoacoustic imaging system | Chengbo Liu; Ying Zhang; Tao Chen; Liangjian Liu; Yin Pan; Hao; Ningbo Chen; Rongkang Gao; Yaguang Ren | invent | China | ZL 2020 1 0451546.4 |
Type of photoacoustic signal processing device and processing method | Zhiqiang Xu; Chengbo Liu; Yinhao Pan | invent | China | ZL 2020 1 1072782.1 |
Optical imaging methods, related devices, and systems | Chengbo Liu; Ke Li; Songjian Wang; Huangxuan Zhao; Liangjian Liu; Ningbo Chen; Liang Song; Zhicheng Liu | invent | China | ZL 2019 1 0844194.6 |
Method and device for monitoring the temperature distribution of the ablation thermal field | Chengbo Liu; Yuan Yuan Bai; Liang Song; Rongqin Zheng; Bing Cong; Kai Li; Xiaojing Gong | invent | China | ZL 2018 1 0836284.6 |
Photoacoustic probe and photoacoustic imaging system | Chengbo Liu; Liang Song; Muyue Xing; Jingqin Chen | invent | China | ZL 2017 1 0046338.4 |
A method for preparing a molecular probe for photoacoustic imaging and photothermal therapy | Jingqin Chen; Chengbo Liu; Liang Song; Xueshen Li; Chihua Fang | invent | China | ZL 2017 1 1219081.4 |
Photoacoustic imaging fixture and the photoacoustic imaging device for its application | Liang Song; Mucong Li; Chengbo Liu; Muyue Xing | invent | China | ZL 2017 1 0116558.X |
Molybdenum disulfide-diao green nanocomposite particles and their preparation methods and applications | Ying Zhu; Liang Song; Zonghai Sheng; Chengbo Liu; Jingqin Chen | invent | China | ZL 2017 1 0373187.3 |
Multimodal imaging system and its imaging methods | Liang Song; Kang Yan; Xiaojing Gong;Riqiang Lin; Chengbo Liu; Xiaoyang Liu | invent | China | ZL 2017 1 0273436.1 |
A dark-field illumination acoustic resolution photoacoustic microscope | Liang Song; Wei Song; Chengbo Liu; Jingqin Chen; Guang Zeng | invent | China | ZL 2015 1 0979703.8 |
Hand photoacoustic imaging probe | Liang Song; Mucong Li; Chengbo Liu;Riqiang Lin | invent | China | ZL 2015 1 0490944.6 |
Type of nanodrug complexes loaded with paclitaxel and their preparation methods | Jingqin Chen; Liang Song; Chengbo Liu;Riqiang Lin | invent | China | ZL 2014 1 0802539.9 |
Hand photoacoustic imaging probe | Liang Song; Chengbo Liu; XiaoSong Bai;Riqiang Lin | invent | China | ZL 2013 1 0323898.1 |
Simple handheld photoacoustic imaging probe | Liang Song; Chengbo Liu; XiaoSong Bai;Riqiang Lin | invent | China | ZL 2013 1 0323890.5 |
Photoacoustic imaging scanning device | Chengbo Liu; Liangjian Liu; Zhenjie Lai; Bin Xu; Zhiqiang Xu | practical | China | ZL 2023 2 0409079.8 |
Photoacoustic signal acquisition device and photoacoustic imaging system | Chengbo Liu; Tao Chen; Liang Song; Ying Zhang; Liangjian Liu; Rongkang Gao; Yaguang Ren; Yanhao Pan | practical | China | ZL 2020 2 2902035.8 |
A photoacoustic microscopy imaging device | Chengbo Liu; Ningbo Chen; Jianhui Zhang; Baiquan Wang; Liangjian Liu | practical | China | ZL 2018 2 2255972.1 |
Photoacoustic imaging probe and photoacoustic imaging system | Chengbo Liu; Yuan Yuan Bai; Liang Song; Xuemin Du | practical | China | ZL 2018 2 1643435.8 |
Type of probe and probe positioning system | Chengbo Liu; Yuan Yuan Bai; Liang Song; Rongqin Zheng; Yan early spring; Kai Li; Bing Cong; Xiaojing Gong | practical | China | ZL 2018 2 1320908.0 |
Photoacoustic imaging system | Chengbo Liu; Liang Song; Yuan Yuan Bai; Rongqin Zheng; Chen Qiu | practical | China | ZL 2018 2 1252102.2 |
An animal eye fixation device for the photoacoustic imaging system | Guangsong Wang; Chengbo Liu; Liang Song; Huangxuan Zhao; Bing Cong | practical | China | ZL 2017 2 1356568.2 |
A photoacoustic microimaging system | Liang Song; Chengbo Liu; Guangsong Wang | practical | China | ZL 2017 2 0131354.9 |
Multimode imaging system | Dong Liang; Xuda Hong; Wei Shi; Xiaojing Gong; Chengbo Liu; Zhanli Hu;Riqiang Lin | practical | China | ZL 2017 2 1812517.6 |
Hand photoacoustic imaging probe | Liang Song; Mucong Li; Chengbo Liu;Riqiang Lin | practical | China | ZL 2015 2 0605201.4 |
Postdoctoral / Research Associate / Research Associate / Visiting Scholar | ||||||
order number | surname and personal name | graduate institutions | In hospital time | In the school position | The current unit | The current position |
1 | Tao Chen | The University of the Chinese Academy of Sciences | 2019.07-2023.08 | Postdoctoral / Associate | Beijing Institute of Technology | Full-time teacher |
2 | Dong He | Xi'an Jiao Tong University | 2018.07-2019.07 | Research assistant | The Hong Kong University of Science and Technology | post-doctoral |
3 | Chen Zhang | SCU | 2018.07-2021.10 | Postdoctoral / Associate | Information occupation in Shenzhen | Full-time teacher |
4 | Xinkuan Jiang | University On The Mountain Of Swallows | 2017.09-2018.05 | Research assistant | Tsinghua University | mechanical engineer |
5 | Bing Cong | Kyoto University | 2017.06-2019.09 | post-doctoral | Innocent laser | medical image |
6 | Huichao Zhou | Zhongshan University | 2017.04-2022.01 | visiting scholar | University of Louvain | post-doctoral |
7 | Yuanyuan Bai | Zhejiang University | 2016.11-2020.01 | Research assistant | Zhongke fly test | Optical engineer |
8 | Guangsong Wang | Central South University | 2016.08-2017.09 | Research assistant | Luohu District construction supervision and housing security center | Level 8 management post staff |
9 | Muyue Xing | Nankai University | 2016.07-2017.11 | Research assistant | Shenzhen University | experimentalist |
10 | Mucong Li | Harbin Institute of Technology | 2014.07-2016.11 | Research assistant | Deepsight Technology Inc | Ultrasound engineer |